Clinical study for evaluation of efficacy of Repairact® to ichthyosis

Chika Ohata, Takahiro Hamada, Fumitake Ono, Yuko Araki, Tatsuyuki Kakuma, Takashi Hashimoto

Research output: Contribution to journalArticlepeer-review


Background: The patients with ichthyosis are annoyed with large scales and xerosis. Topical moisturizing agent is important for the treatment of ichthyosis. Methods: We studied the efficacy of Repairact® to 18 patients with ichthyosis, who visited Department of Dermatology in Kurume University between May and December in 2013, in terms of clinical efficacy including erythema, edema/papule, exudate/crust, scratch mark, lichenification, scale, and pruritus, using Propeto® as a control ointment. Results: We found that Repairact® significantly improved scale more than Propeto® did. Repairact® also tended to improve pruritus than Propeto® did. Conclusions: These results raised the possibility that Repairact® could be effective on other dermatitis associated with xerosis.

Original languageEnglish
Pages (from-to)175-180
Number of pages6
JournalJapanese Pharmacology and Therapeutics
Issue number2
Publication statusPublished - 2014
Externally publishedYes


  • Ichthyosis
  • Pruritus
  • Repairact®
  • Scale
  • Xerosis

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)


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