Clinical study for evaluation of efficacy of Repairact® to ichthyosis

Background: The patients with ichthyosis are annoyed with large scales and xerosis. Topical moisturizing agent is important for the treatment of ichthyosis. Methods: We studied the efficacy of Repairact® to 18 patients with ichthyosis, who visited Department of Dermatology in Kurume University between May and December in 2013, in terms of clinical efficacy including erythema, edema/papule, exudate/crust, scratch mark, lichenification, scale, and pruritus, using Propeto® as a control ointment. Results: We found that Repairact® significantly improved scale more than Propeto® did. Repairact® also tended to improve pruritus than Propeto® did. Conclusions: These results raised the possibility that Repairact® could be effective on other dermatitis associated with xerosis.