Cloning and chromosome mapping of human and chicken Iroquois (Irx) genes

K. Ogura; K. Matsumoto; A. Kuroiwa; T. Isobe; T. Otoguro; V. Jurecic; A. Baldini; Y. Matsuda; Toshihiko Ogura

doi:10.1159/000056921

Cloning and chromosome mapping of human and chicken Iroquois (Irx) genes

K. Ogura, K. Matsumoto, A. Kuroiwa, T. Isobe, T. Otoguro, V. Jurecic, A. Baldini, Y. Matsuda, Toshihiko Ogura

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Three highly homologous homeobox genes (caupolican, araucan and mirror) have been identified in Drosophila. These genes belong to the novel Iroquois complex, which acts as a pre-pattern molecule in Drosophila neurogenesis. Recently several vertebrate Iroquois homologues (Irx) were isolated and found to be involved in pattern formation of various tissues. Here we report cytogenetic mapping of four human and five chicken Iroquois genes by FISH. Our findings revealed that vertebrate Irx genes are clustered at two different loci.

Original language	English
Pages (from-to)	320-325
Number of pages	6
Journal	Cytogenetics and Cell Genetics
Volume	92
Issue number	3-4
DOIs	https://doi.org/10.1159/000056921
Publication status	Published - 2001
Externally published	Yes

ASJC Scopus subject areas

Genetics
Cell Biology

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title = "Cloning and chromosome mapping of human and chicken Iroquois (Irx) genes",

abstract = "Three highly homologous homeobox genes (caupolican, araucan and mirror) have been identified in Drosophila. These genes belong to the novel Iroquois complex, which acts as a pre-pattern molecule in Drosophila neurogenesis. Recently several vertebrate Iroquois homologues (Irx) were isolated and found to be involved in pattern formation of various tissues. Here we report cytogenetic mapping of four human and five chicken Iroquois genes by FISH. Our findings revealed that vertebrate Irx genes are clustered at two different loci.",

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T1 - Cloning and chromosome mapping of human and chicken Iroquois (Irx) genes

AU - Ogura, K.

AU - Matsumoto, K.

AU - Kuroiwa, A.

AU - Isobe, T.

AU - Otoguro, T.

AU - Jurecic, V.

AU - Baldini, A.

AU - Matsuda, Y.

AU - Ogura, Toshihiko

PY - 2001

Y1 - 2001

N2 - Three highly homologous homeobox genes (caupolican, araucan and mirror) have been identified in Drosophila. These genes belong to the novel Iroquois complex, which acts as a pre-pattern molecule in Drosophila neurogenesis. Recently several vertebrate Iroquois homologues (Irx) were isolated and found to be involved in pattern formation of various tissues. Here we report cytogenetic mapping of four human and five chicken Iroquois genes by FISH. Our findings revealed that vertebrate Irx genes are clustered at two different loci.

AB - Three highly homologous homeobox genes (caupolican, araucan and mirror) have been identified in Drosophila. These genes belong to the novel Iroquois complex, which acts as a pre-pattern molecule in Drosophila neurogenesis. Recently several vertebrate Iroquois homologues (Irx) were isolated and found to be involved in pattern formation of various tissues. Here we report cytogenetic mapping of four human and five chicken Iroquois genes by FISH. Our findings revealed that vertebrate Irx genes are clustered at two different loci.

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JO - Cytogenetic and Genome Research

JF - Cytogenetic and Genome Research

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ER -

Cloning and chromosome mapping of human and chicken Iroquois (Irx) genes

Abstract

ASJC Scopus subject areas

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