TY - JOUR
T1 - Cloning and functional analysis of cis-prenyltransferase from Thermobifida fusca
AU - Ambo, Takanori
AU - Noike, Motoyoshi
AU - Kurokawa, Hirofumi
AU - Koyama, Tanetoshi
N1 - Funding Information:
This work was supported by Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan.
PY - 2009/6
Y1 - 2009/6
N2 - cis-Prenyltransferase catalyzes the synthesis of Z,E-mixed prenyl diphosphates by a condensation of isopentenyl diphosphate to an allylic diphosphate. A novel gene encoding a cis-prenyltransferase is cloned from Thermobifida fusca. It showed a unique substrate specificity accepting dimethylallyl diphosphate as a shortest allylic substrate, and synthesizes polyprenyl products up to C70.
AB - cis-Prenyltransferase catalyzes the synthesis of Z,E-mixed prenyl diphosphates by a condensation of isopentenyl diphosphate to an allylic diphosphate. A novel gene encoding a cis-prenyltransferase is cloned from Thermobifida fusca. It showed a unique substrate specificity accepting dimethylallyl diphosphate as a shortest allylic substrate, and synthesizes polyprenyl products up to C70.
KW - Actinomycete
KW - Isoprenoid biosynthesis
KW - Prenyltransferase
KW - Sugar carrier lipid biosynthesis
KW - Thermobifida fusca
UR - http://www.scopus.com/inward/record.url?scp=65549089150&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=65549089150&partnerID=8YFLogxK
U2 - 10.1016/j.jbiosc.2009.02.006
DO - 10.1016/j.jbiosc.2009.02.006
M3 - Article
C2 - 19447338
AN - SCOPUS:65549089150
SN - 1389-1723
VL - 107
SP - 620
EP - 622
JO - Journal of Bioscience and Bioengineering
JF - Journal of Bioscience and Bioengineering
IS - 6
ER -