Coincidence of Large Adrenal Cyst and Prominent Hyporeninemic Hyperaldosteronism

Takaaki Sakaue, Yosuke Okuno, Kosuke Mukai, Shingo Fujita, Junji Kozawa, Hitoshi Nishizawa, Taka Aki Matsuoka, Hiromi Iwahashi, Maeda Norikazu, Yuto Yamazaki, Hironobu Sasano, Michio Otsuki, Iichiro Shimomura

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A 67-year-old Japanese woman who had end-stage renal disease was referred to our hospital for kidney transplantation. Abdominal CT revealed a large adrenal mass with inhomogeneity. She had a history of hospitalization for stroke and heart failure and exhibited prominent hyporeninemic hyperaldosteronism. Histological examination of the resected tumor with anti-CYP11B2 antibody indicated that she had a vascular endothelial cyst with primary aldosteronism (PA) due to multiple adrenocortical micronodules. This report implicates the pathological interaction between adrenal vascular cysts and PA-mediated vascular damage of the adrenal vein.

Original languageEnglish
Article number8860498
JournalCase Reports in Endocrinology
Publication statusPublished - 2021


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