Colorimetric calcium-response of β-lactosylated μ-oxo-bis-[5,15- meso-diphenylporphyrinatoiron(III)]

Teruaki Hasegawa, Munenori Numata, Masayoshi Asai, Masayuki Takeuchi, Seiji Shinkai

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

β-Lactosylated 5,15-meso-diphenylporphyrinatoiron(III) chloride was prepared by ironization of the corresponding free base porphyrin having acetylated lactoside-units followed by deacetylation with ammonia in a water-methanol mixture. The resultant 5,15-meso-bis(β-lactosylphenyl) porphyrinatoiron(III) chloride showed unique colorimetric response to calcium cation. This colorimetric response is calcium-specific and no other cations, such as sodium, potassium, or magnesium ions induced such colorimetric response. Lines of evidence including UV-vis spectra under different conditions and TEM images strongly indicate that interdigitations of the corresponding μ-oxo-dimers are responsible for this colorimetric change.

Original languageEnglish
Pages (from-to)7783-7788
Number of pages6
JournalTetrahedron
Volume61
Issue number32
DOIs
Publication statusPublished - 2005 Aug 8
Externally publishedYes

Keywords

  • Carbohydrate-carbohydrate interactions

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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