We investigated the combined effects of perceptual grouping cues (proximity and contour closure/proximity and orientation similarity) on object representation, using motion-induced blindness, a phenomenon in which salient visual stimuli perceptually disappear when surrounded by moving patterns. We presented as visual targets two stimuli in which a solid square was embedded in an outlined square. Participants reported whether the targets disappeared independently or simultaneously. The results showed that a relatively high proximity cue (with a 0.2-deg separation between the targets) modulated the perceptions of the independent or simultaneous disappearances of targets, regardless of other grouping cues. The contour closure cue modulated these disappearances in the 0.4- to 0.8-deg separations. Finally, the orientation similarity cue began to modulate these disappearances in the 0.6- to 0.8-deg separations. We suggest that the separation between the visual stimuli modulates the combined effects of perceptual grouping cues on complete object representation.