Comparison of three surgical procedures for colpopoiesis in patients with Mayer-Rokitansky-Küster-Hauser syndrome

Mayer-Rokitansky-Küster-Hauser (M-R-K-H) syndrome is a rare congenital anomaly of the female genital tract. A number of techniques have been described for the formation of a neovagina, however, a standardized treatment does not yet exist. To evaluate three surgical procedures for colpopoiesis in patients with M-R-K-H syndrome, we design a retrospective study based on record of clinical data in our university hospital. Eighteen patients with M-R-K-H syndrome were performed colpopoiesis by Ruge's, McIndoe's and laparoscopically assisted Davydov's procedures. We compare with three surgical procedures in terms of operative success rate, operation time, total bleeding loss during operation, perioperative complication rate, and long-term complications. The postoperative vaginal depth showed no significant difference among the three procedures. Operation success rate was 50.0% in Ruge's procedure, 88.9% in McIndoe's procedure, and 100% in laparoscopically assisted Davydov's procedure. The duration of McIndoe's and laparoscopically assisted Davydov's procedure was significantly shorter than that of Ruge's procedure. The total bleeding loss in McIndoe's and laparoscopically assisted Davydov's procedure was significantly less than that in Ruge's procedure. The duration of hospitalization for Ruge's and McIndoe's procedure was significantly longer than that for laparoscopically assisted Davydov's procedure. With regard to long-term complications, two cases that underwent Ruge's procedure had severe neovaginal prolapse, and one case that underwent McIndoe's procedure had mild stenosis. One case that underwent laparoscopically assisted Davydov's procedure had mild granulation. In conclusion, laparoscopically assisted Davydov's procedure is comparatively successful and safe for colpopoiesis of M-R-K-H patients.