Complete Response to Neoadjuvant Chemotherapy with Imatinib of a Large Gastric GIST-A Case Report

Tomomi Kawana; Hirofumi Imoto; Naoki Tanaka; Takeshi Aoki; Akihiro Yamamura; Takahiro Tsuchiya; Norihiko Sugisawa; Hiromichi Sasaki; Takanori Morikawa; Fumiyoshi Fujishima; Shinobu Onuma; Takashi Kamei; Michiaki Unno

Complete Response to Neoadjuvant Chemotherapy with Imatinib of a Large Gastric GIST-A Case Report

Tomomi Kawana, Hirofumi Imoto, Naoki Tanaka, Takeshi Aoki, Akihiro Yamamura, Takahiro Tsuchiya, Norihiko Sugisawa, Hiromichi Sasaki, Takanori Morikawa, Fumiyoshi Fujishima, Shinobu Onuma, Takashi Kamei, Michiaki Unno

Research output: Contribution to journal › Article › peer-review

Abstract

A 54-year-old woman was presented with the intraabdominal mass to our hospital. Abdominal CT showed 22 cm tumor of the stomach with invasion to the pancreas and the spleen. Upper GI endoscopy showed submucosal tumor at the stomach body, and endoscopic US showed low echoic tumor. The tumor was diagnosed as gastric GIST by biopsy with c-kit positive cells. After 4 months of neoadjuvant therapy with imatinib, she underwent total gastrectomy, distal pancreatectomy and splenectomy. Histopathologically, there were no viable tumor cells in the resected specimen. The patient has no evidence of recurrence at 8 months post operation.

Original language	English
Pages (from-to)	1749-1751
Number of pages	3
Journal	Gan to kagaku ryoho. Cancer & chemotherapy
Volume	48
Issue number	13
Publication status	Published - 2021 Dec 1

ASJC Scopus subject areas

Medicine(all)

Cite this

@article{f3bb60f81db84c4fab50500496ef4c01,

title = "Complete Response to Neoadjuvant Chemotherapy with Imatinib of a Large Gastric GIST-A Case Report",

abstract = "A 54-year-old woman was presented with the intraabdominal mass to our hospital. Abdominal CT showed 22 cm tumor of the stomach with invasion to the pancreas and the spleen. Upper GI endoscopy showed submucosal tumor at the stomach body, and endoscopic US showed low echoic tumor. The tumor was diagnosed as gastric GIST by biopsy with c-kit positive cells. After 4 months of neoadjuvant therapy with imatinib, she underwent total gastrectomy, distal pancreatectomy and splenectomy. Histopathologically, there were no viable tumor cells in the resected specimen. The patient has no evidence of recurrence at 8 months post operation.",

author = "Tomomi Kawana and Hirofumi Imoto and Naoki Tanaka and Takeshi Aoki and Akihiro Yamamura and Takahiro Tsuchiya and Norihiko Sugisawa and Hiromichi Sasaki and Takanori Morikawa and Fumiyoshi Fujishima and Shinobu Onuma and Takashi Kamei and Michiaki Unno",

year = "2021",

month = dec,

day = "1",

language = "English",

volume = "48",

pages = "1749--1751",

journal = "Japanese Journal of Cancer and Chemotherapy",

issn = "0385-0684",

publisher = "Japanese Journal of Cancer and Chemotherapy Publishers Inc.",

number = "13",

}

TY - JOUR

T1 - Complete Response to Neoadjuvant Chemotherapy with Imatinib of a Large Gastric GIST-A Case Report

AU - Kawana, Tomomi

AU - Imoto, Hirofumi

AU - Tanaka, Naoki

AU - Aoki, Takeshi

AU - Yamamura, Akihiro

AU - Tsuchiya, Takahiro

AU - Sugisawa, Norihiko

AU - Sasaki, Hiromichi

AU - Morikawa, Takanori

AU - Fujishima, Fumiyoshi

AU - Onuma, Shinobu

AU - Kamei, Takashi

AU - Unno, Michiaki

PY - 2021/12/1

Y1 - 2021/12/1

N2 - A 54-year-old woman was presented with the intraabdominal mass to our hospital. Abdominal CT showed 22 cm tumor of the stomach with invasion to the pancreas and the spleen. Upper GI endoscopy showed submucosal tumor at the stomach body, and endoscopic US showed low echoic tumor. The tumor was diagnosed as gastric GIST by biopsy with c-kit positive cells. After 4 months of neoadjuvant therapy with imatinib, she underwent total gastrectomy, distal pancreatectomy and splenectomy. Histopathologically, there were no viable tumor cells in the resected specimen. The patient has no evidence of recurrence at 8 months post operation.

AB - A 54-year-old woman was presented with the intraabdominal mass to our hospital. Abdominal CT showed 22 cm tumor of the stomach with invasion to the pancreas and the spleen. Upper GI endoscopy showed submucosal tumor at the stomach body, and endoscopic US showed low echoic tumor. The tumor was diagnosed as gastric GIST by biopsy with c-kit positive cells. After 4 months of neoadjuvant therapy with imatinib, she underwent total gastrectomy, distal pancreatectomy and splenectomy. Histopathologically, there were no viable tumor cells in the resected specimen. The patient has no evidence of recurrence at 8 months post operation.

UR - http://www.scopus.com/inward/record.url?scp=85123814315&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85123814315&partnerID=8YFLogxK

M3 - Article

C2 - 35046318

AN - SCOPUS:85123814315

SN - 0385-0684

VL - 48

SP - 1749

EP - 1751

JO - Japanese Journal of Cancer and Chemotherapy

JF - Japanese Journal of Cancer and Chemotherapy

IS - 13

ER -

Complete Response to Neoadjuvant Chemotherapy with Imatinib of a Large Gastric GIST-A Case Report

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this