TY - JOUR
T1 - Complications associated with catheter ablation in patients with atrial fibrillation
T2 - A report from the jroad-dpc study
AU - Yokoyama, Yasuhiro
AU - Miyamoto, Koji
AU - Nakai, Michikazu
AU - Sumita, Yoko
AU - Ueda, Nobuhiko
AU - Nakajima, Kenzaburo
AU - Kamakura, Tsukasa
AU - Wada, Mitsuru
AU - Yamagata, Kenichiro
AU - Ishibashi, Kohei
AU - Inoue, Yuko
AU - Nagase, Satoshi
AU - Noda, Takashi
AU - Aiba, Takeshi
AU - Miyamoto, Yoshihiro
AU - Yasuda, Satoshi
AU - Kusano, Kengo
N1 - Funding Information:
The study was partly supported by the Intramural Research Fund 17 (Dr Kusano) for Cardiovascular Diseases of the National Cerebral and Cardiovascular Center.
Publisher Copyright:
© 2021 The Authors.
PY - 2021/6/1
Y1 - 2021/6/1
N2 - BACKGROUND: Aging is one of the major concerns and determinants of the indications for catheter ablation (CA) for atrial fibril-lation. This study aimed to assess the safety of CA in older patients with atrial fibrillation undergoing CA. METHODS AND RESULTS: The JROAD-DPC (Japanese Registry of All Cardiac and Vascular Diseases-Diagnosis Procedure Combination) is a nationwide claims database using data from the Japanese Diagnosis Procedure Combination/Per Diem Payment System. Among 6 632 484 records found between April 2012 and March 2018 from 1058 hospitals, 135 299 patients with atrial fibrillation (aged 65±10 years, 38 952 women) who underwent CA in 456 hospitals were studied and divided into the following age groups: <60, 60 to 64, 65 to 69, 70 to 74, 75 to 79, 80 to 84, and ≥85 years. The overall in-hospital complication rate was 3.4% (cardiac tamponade 1.2%), and in-hospital mortality was 0.04%. Older patients had a higher prevalence of women, lower body mass index, and a higher burden of comorbidities such as hypertension, and all of those characteristics were predictors for complications in multivariate analysis. A multivariate adjusted odds ratio revealed that increased age was independently and significantly associated with overall complications (60–64 years, 1.19; 65–69 years, 1.29; 70–74 years, 1.57; 75–79 years, 1.63; 80–84 years, 1.90; and ≥85 years, 2.86; the reference was <60 years). CONCLUSIONS: The nationwide JROAD-DPC database demonstrated that the frequency of complications following CA in patients with atrial fibrillation increased according to age.
AB - BACKGROUND: Aging is one of the major concerns and determinants of the indications for catheter ablation (CA) for atrial fibril-lation. This study aimed to assess the safety of CA in older patients with atrial fibrillation undergoing CA. METHODS AND RESULTS: The JROAD-DPC (Japanese Registry of All Cardiac and Vascular Diseases-Diagnosis Procedure Combination) is a nationwide claims database using data from the Japanese Diagnosis Procedure Combination/Per Diem Payment System. Among 6 632 484 records found between April 2012 and March 2018 from 1058 hospitals, 135 299 patients with atrial fibrillation (aged 65±10 years, 38 952 women) who underwent CA in 456 hospitals were studied and divided into the following age groups: <60, 60 to 64, 65 to 69, 70 to 74, 75 to 79, 80 to 84, and ≥85 years. The overall in-hospital complication rate was 3.4% (cardiac tamponade 1.2%), and in-hospital mortality was 0.04%. Older patients had a higher prevalence of women, lower body mass index, and a higher burden of comorbidities such as hypertension, and all of those characteristics were predictors for complications in multivariate analysis. A multivariate adjusted odds ratio revealed that increased age was independently and significantly associated with overall complications (60–64 years, 1.19; 65–69 years, 1.29; 70–74 years, 1.57; 75–79 years, 1.63; 80–84 years, 1.90; and ≥85 years, 2.86; the reference was <60 years). CONCLUSIONS: The nationwide JROAD-DPC database demonstrated that the frequency of complications following CA in patients with atrial fibrillation increased according to age.
KW - Atrial fibrillation
KW - Catheter ablation
KW - Complications
KW - Japanese Registry of All Cardiac and Vascular Diseases
KW - Older
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U2 - 10.1161/JAHA.120.019701
DO - 10.1161/JAHA.120.019701
M3 - Article
C2 - 34041920
AN - SCOPUS:85107390916
SN - 2047-9980
VL - 10
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
IS - 11
M1 - e019701
ER -