Computational modeling of beam-customization devices for heavy-charged-particle radiotherapy

Nobuyuki Kanematsu, Shunsuke Yonai, Azusa Ishizaki, Masami Torikoshi

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


A model for beam customization with collimators and a range-compensating filter based on the phase-space theory for beam transport is presented for dose distribution calculation in the treatment planning of radiotherapy with protons and heavier ions. Independent handling of pencil beams in conventional pencil-beam algorithms causes unphysical collimator-height dependence in the middle of large fields, which is resolved by the framework comprised of generation, transport, collimation, regeneration, range-compensation and edge-sharpening processes with a matrix of pencil beams. The model was verified to be consistent with measurement and analytic estimation at a submillimeter level in the penumbra of individual collimators with a combinational-collimated carbon-ion beam. The model computation is fast, accurate and readily applicable to pencil-beam algorithms in treatment planning with the capability of combinational collimation to make the best use of the beam-customization devices.

Original languageEnglish
Pages (from-to)3113-3127
Number of pages15
JournalPhysics in medicine and biology
Issue number12
Publication statusPublished - 2008 Jun 21
Externally publishedYes

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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