Abstract
A model for beam customization with collimators and a range-compensating filter based on the phase-space theory for beam transport is presented for dose distribution calculation in the treatment planning of radiotherapy with protons and heavier ions. Independent handling of pencil beams in conventional pencil-beam algorithms causes unphysical collimator-height dependence in the middle of large fields, which is resolved by the framework comprised of generation, transport, collimation, regeneration, range-compensation and edge-sharpening processes with a matrix of pencil beams. The model was verified to be consistent with measurement and analytic estimation at a submillimeter level in the penumbra of individual collimators with a combinational-collimated carbon-ion beam. The model computation is fast, accurate and readily applicable to pencil-beam algorithms in treatment planning with the capability of combinational collimation to make the best use of the beam-customization devices.
| Original language | English |
|---|---|
| Pages (from-to) | 3113-3127 |
| Number of pages | 15 |
| Journal | Physics in medicine and biology |
| Volume | 53 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2008 Jun 21 |
| Externally published | Yes |
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging