Concise synthesis of the C15-C38 fragment of okadaic acid: Application of the Suzuki-Miyaura reaction to spiroacetal synthesis

Haruhiko Fuwa, Keita Sakamoto, Takashi Muto, Makoto Sasaki

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

A concise synthetic entry to the C15-C38 fragment of okadaic acid by exploiting a Suzuki-Miyaura reaction for the rapid assembly of the spiroacetal substructures has been developed. The present synthesis was completed in 19 linear steps from a commercially available material, showcasing the efficiency of our synthetic strategy.

Original languageEnglish
Pages (from-to)366-369
Number of pages4
JournalOrganic Letters
Volume17
Issue number2
DOIs
Publication statusPublished - 2015 Jan 16

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