Confabulations in episodic memory are associated with delusions in Alzheimer's disease

Eunjoo Lee; Kenichi Meguro; Ryusaku Hashimoto; Mitsue Meguro; Hiroshi Ishii; Satoshi Yamaguchi; Etsuro Mori

doi:10.1177/0891988706292760

Confabulations in episodic memory are associated with delusions in Alzheimer's disease

Eunjoo Lee, Kenichi Meguro, Ryusaku Hashimoto, Mitsue Meguro, Hiroshi Ishii, Satoshi Yamaguchi, Etsuro Mori

New Industry Creation Hatchery Center (NICHe)

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9 Citations (Scopus)

Abstract

Although confabulations and delusions are observed in Alzheimer's disease, the relationship between the 2 has not been fully investigated. This study involved 50 patients with Alzheimer's disease and 10 healthy participants. After the patients were divided into delusional and nondelusional groups, confabulations and cognitive function were assessed. No confabulations appeared in the healthy participants, and only patients with Alzheimer's disease showed confabulations. The delusional group produced more confabulations on episodic subjects than on semantic subjects. There was a correlation between cognitive impairment and confabulations in semantic memory. These findings suggest that different mechanisms are involved in confabulations between semantic and episodic memories.

Original language	English
Pages (from-to)	34-40
Number of pages	7
Journal	Journal of Geriatric Psychiatry and Neurology
Volume	20
Issue number	1
DOIs	https://doi.org/10.1177/0891988706292760
Publication status	Published - 2007 Mar

Keywords

Alzheimer's disease
Confabulation
Delusion

ASJC Scopus subject areas

Clinical Neurology
Geriatrics and Gerontology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/0891988706292760

Cite this

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abstract = "Although confabulations and delusions are observed in Alzheimer's disease, the relationship between the 2 has not been fully investigated. This study involved 50 patients with Alzheimer's disease and 10 healthy participants. After the patients were divided into delusional and nondelusional groups, confabulations and cognitive function were assessed. No confabulations appeared in the healthy participants, and only patients with Alzheimer's disease showed confabulations. The delusional group produced more confabulations on episodic subjects than on semantic subjects. There was a correlation between cognitive impairment and confabulations in semantic memory. These findings suggest that different mechanisms are involved in confabulations between semantic and episodic memories.",

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AU - Lee, Eunjoo

AU - Meguro, Kenichi

AU - Hashimoto, Ryusaku

AU - Meguro, Mitsue

AU - Ishii, Hiroshi

AU - Yamaguchi, Satoshi

AU - Mori, Etsuro

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AB - Although confabulations and delusions are observed in Alzheimer's disease, the relationship between the 2 has not been fully investigated. This study involved 50 patients with Alzheimer's disease and 10 healthy participants. After the patients were divided into delusional and nondelusional groups, confabulations and cognitive function were assessed. No confabulations appeared in the healthy participants, and only patients with Alzheimer's disease showed confabulations. The delusional group produced more confabulations on episodic subjects than on semantic subjects. There was a correlation between cognitive impairment and confabulations in semantic memory. These findings suggest that different mechanisms are involved in confabulations between semantic and episodic memories.

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Confabulations in episodic memory are associated with delusions in Alzheimer's disease

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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