Coronary artery bypass grafting in a patient with hemophilia B: continuous recombinant factor IX infusion as per the Japanese guidelines for replacement therapy

Tomoyuki Suzuki; Shunsuke Kawamoto; Kiichiro Kumagai; Osamu Adachi; Keisuke Kanda; Masaaki Ishikawa; Yoko Okitsu; Hideo Harigae; Shin Kurosawa; Yoshikatsu Saiki

doi:10.1007/s11748-014-0509-4

Coronary artery bypass grafting in a patient with hemophilia B: continuous recombinant factor IX infusion as per the Japanese guidelines for replacement therapy

Tomoyuki Suzuki, Shunsuke Kawamoto, Kiichiro Kumagai, Osamu Adachi, Keisuke Kanda, Masaaki Ishikawa, Yoko Okitsu, Hideo Harigae, Shin Kurosawa, Yoshikatsu Saiki

Tohoku University

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

We herein report our experience of successfully managing the hemostatic system by controlling serum factor IX levels throughout the perioperative period in a patient with hemophilia B. Coronary artery bypass grafting with cardiopulmonary bypass was planned for a 52-year-old man with moderate severity of hemophilia B. During surgery, recombinant factor IX (rFIX; BeneFIX^® Pfizer Japan inc., Tokyo, Japan) was administered by bolus infusion followed by continuous infusion as per the guidelines of the Japanese Society on Thrombosis and Hemostasis. The operative course was uneventful without any considerable bleeding or complications.

Original language	English
Pages (from-to)	481-483
Number of pages	3
Journal	General Thoracic and Cardiovascular Surgery
Volume	64
Issue number	8
DOIs	https://doi.org/10.1007/s11748-014-0509-4
Publication status	Published - 2016 Aug 1

Keywords

Continuous infusion
Coronary artery bypass grafting
Hemophilia B
Recombinant factor IX

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10.1007/s11748-014-0509-4

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Suzuki, T., Kawamoto, S., Kumagai, K., Adachi, O., Kanda, K., Ishikawa, M., Okitsu, Y., Harigae, H., Kurosawa, S., & Saiki, Y. (2016). Coronary artery bypass grafting in a patient with hemophilia B: continuous recombinant factor IX infusion as per the Japanese guidelines for replacement therapy. General Thoracic and Cardiovascular Surgery, 64(8), 481-483. https://doi.org/10.1007/s11748-014-0509-4

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abstract = "We herein report our experience of successfully managing the hemostatic system by controlling serum factor IX levels throughout the perioperative period in a patient with hemophilia B. Coronary artery bypass grafting with cardiopulmonary bypass was planned for a 52-year-old man with moderate severity of hemophilia B. During surgery, recombinant factor IX (rFIX; BeneFIX{\textregistered} Pfizer Japan inc., Tokyo, Japan) was administered by bolus infusion followed by continuous infusion as per the guidelines of the Japanese Society on Thrombosis and Hemostasis. The operative course was uneventful without any considerable bleeding or complications.",

keywords = "Continuous infusion, Coronary artery bypass grafting, Hemophilia B, Recombinant factor IX",

author = "Tomoyuki Suzuki and Shunsuke Kawamoto and Kiichiro Kumagai and Osamu Adachi and Keisuke Kanda and Masaaki Ishikawa and Yoko Okitsu and Hideo Harigae and Shin Kurosawa and Yoshikatsu Saiki",

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Suzuki, T, Kawamoto, S, Kumagai, K, Adachi, O, Kanda, K, Ishikawa, M, Okitsu, Y, Harigae, H, Kurosawa, S & Saiki, Y 2016, 'Coronary artery bypass grafting in a patient with hemophilia B: continuous recombinant factor IX infusion as per the Japanese guidelines for replacement therapy', General Thoracic and Cardiovascular Surgery, vol. 64, no. 8, pp. 481-483. https://doi.org/10.1007/s11748-014-0509-4

Coronary artery bypass grafting in a patient with hemophilia B: continuous recombinant factor IX infusion as per the Japanese guidelines for replacement therapy. / Suzuki, Tomoyuki; Kawamoto, Shunsuke; Kumagai, Kiichiro et al.
In: General Thoracic and Cardiovascular Surgery, Vol. 64, No. 8, 01.08.2016, p. 481-483.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Coronary artery bypass grafting in a patient with hemophilia B

T2 - continuous recombinant factor IX infusion as per the Japanese guidelines for replacement therapy

AU - Suzuki, Tomoyuki

AU - Kawamoto, Shunsuke

AU - Kumagai, Kiichiro

AU - Adachi, Osamu

AU - Kanda, Keisuke

AU - Ishikawa, Masaaki

AU - Okitsu, Yoko

AU - Harigae, Hideo

AU - Kurosawa, Shin

AU - Saiki, Yoshikatsu

PY - 2016/8/1

Y1 - 2016/8/1

N2 - We herein report our experience of successfully managing the hemostatic system by controlling serum factor IX levels throughout the perioperative period in a patient with hemophilia B. Coronary artery bypass grafting with cardiopulmonary bypass was planned for a 52-year-old man with moderate severity of hemophilia B. During surgery, recombinant factor IX (rFIX; BeneFIX® Pfizer Japan inc., Tokyo, Japan) was administered by bolus infusion followed by continuous infusion as per the guidelines of the Japanese Society on Thrombosis and Hemostasis. The operative course was uneventful without any considerable bleeding or complications.

AB - We herein report our experience of successfully managing the hemostatic system by controlling serum factor IX levels throughout the perioperative period in a patient with hemophilia B. Coronary artery bypass grafting with cardiopulmonary bypass was planned for a 52-year-old man with moderate severity of hemophilia B. During surgery, recombinant factor IX (rFIX; BeneFIX® Pfizer Japan inc., Tokyo, Japan) was administered by bolus infusion followed by continuous infusion as per the guidelines of the Japanese Society on Thrombosis and Hemostasis. The operative course was uneventful without any considerable bleeding or complications.

KW - Continuous infusion

KW - Coronary artery bypass grafting

KW - Hemophilia B

KW - Recombinant factor IX

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Coronary artery bypass grafting in a patient with hemophilia B: continuous recombinant factor IX infusion as per the Japanese guidelines for replacement therapy

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