Correlation of extract composition on antioxidant activity of electrospun polyvinylpyrrolidone/bassela rubra linn leaf extract composite

Eka Lutfi Septiani, Azmi Alvian Gabriel, Okky Putri Prastuti, Defi Nur Indahsari, Ervina Diah Ariyanti, Siti Machmudah, Sugeng Winardi, Wahyudiono, Hideki Kanda, Motonobu Goto

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Nanofiber through electrospinning process has been developed as a promising material for wound dressing due to its large porosity and high surface area. This characteristic of nanofiber provides an adequate gas permeability surrounding the wound which prevents the healing failure. The best wound dressing not only maintain a wound to have a good gas permeability but also to have an active agent giving an antibacterial and antiinflammation property. This research aims to combine a synthetic polymer and active agent, polyvinylpyrrolidone (PVP) and Bassela rubra linn leaf extract (BRLE), become nanofibrous material. The electrospinning process was conducted in two steps. The first step is to obtain the best voltage of PVP electrospinning by using the voltage of 10, 12, 15, 17 kV. The other step is combining PVP to 2%, 5%, 8% of BRLE. The first step shows the best operation condition is using 12 kV. Hence, it is used to obtain nanofiber with different BRLE percentage. Based on 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, the result indicates that increase the BRLE composition will rise the antioxidant activity because of the smaller diameter size.

Original languageEnglish
Title of host publicationAdvanced Materials for Renewable Energy
EditorsAripriharta Aripriharta, Aripriharta Aripriharta, Poppy Puspitasari, Poppy Puspitasari
PublisherTrans Tech Publications Ltd
Pages122-127
Number of pages6
ISBN (Print)9783035716276
DOIs
Publication statusPublished - 2020
EventAnnual International Conference on Renewable Energy, ICORE 2019 - Malang, Indonesia
Duration: 2019 Aug 92019 Aug 10

Publication series

NameKey Engineering Materials
Volume851 KEM
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Conference

ConferenceAnnual International Conference on Renewable Energy, ICORE 2019
Country/TerritoryIndonesia
CityMalang
Period19/8/919/8/10

Keywords

  • Antioxidant activity
  • Basella rubra linn (binahong) extract
  • Electrospinning
  • Nanofiber

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