Correlation of pulmonary perfusion volume analysis with pulmonary function in emphysema

T. Kaneta, T. Yamazaki, S. Maruoka, Y. Abe, Y. Takai, S. Takahashi, S. Yamada

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Pulmonary perfusion single photon emission tomography with 99mTc MAA was performed on 13 pulmonary emphysema patients and 6 controls. We calculated perfusion volume with lower 10%, 20%, 30%, 40% and 50% of the highest counts/boxels in the lung cut-off. And perfusion index (PI) was defined as follows; PI = ((A% cut-off volume) - (B% cut-off volume))/(A% cut-off volume); A and B take 10 to 50, A < B. The correlation of each PI and pulmonary function test results (FEV1, FEV1%, VC, VC%, FVC, FVC%, PaO2 and PaCO2) was examined. There were significant correlation between every PI and FEV1 or FEV1% (p < 0.05), and any PI had no significant correlation with other functional results. When A = 10 and B = 40, the PI showed the best correlation with FEV1 (r = 0.680) and FEV1% (r = 0.830). And the PI showed an increasing tendency along with the rise of the emphysema severity. The PI may have the clinical utility of the evaluation of pulmonary function. Moreover, we showed the lung CT painted the area where the uptake counts/boxels was more than 10% and less than 40% of the highest counts/boxels. This makes it easy to understand the severe emphysematous area.

Original languageEnglish
Pages (from-to)359-364
Number of pages6
JournalKaku igaku. The Japanese journal of nuclear medicine
Issue number4
Publication statusPublished - 2000 Jul


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