Cortical bone response toward nanosecond-pulsed laser-treated zirconia implant surfaces

Masatsugu Hirota, Tomohiro Harai, Shinji Ishibashi, Masayoshi Mizutani, Tohru Hayakawa

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Two type of partially stabilized zirconia, namely yttria-stabilized tetragonal zirconia polycrystals (Y-TZP) and ceria-stabilized tetragonal zirconia polycrystals including aluminum oxide nanocomposite (Ce-TZP), were irradiated by nanosecond-pulsed Nd:YAG laser and the regular structure with concave and convex of each 30 μm width and 30 μm depth were prepared on both surfaces. In the case of Ce-TZP, the surface was changed to be black after laser irradiation. EDX measurement revealed the reduction of more amounts of oxygen atoms on Ce-TZP compared to Y-TZP. Laser irradiated zirconia implants were inserted into the bone defects of rat femur during 4 weeks. As a control, large grid sandblasted and acid etching (blastedHF) implant was used. Laser treatment for Y-TZP provided greater degree of bone-implant contact ratio than blastedHF treated Y-TZP (p<0.05). In the case of Ce-TZP, however, laser treatment showed no clear effect on bone response.

Original languageEnglish
Article numberJST.JSTAGE/dmj/2018-153
Pages (from-to)444-451
Number of pages8
JournalDental Materials Journal
Issue number3
Publication statusPublished - 2019


  • Bone-to-implant contact
  • Nanosecond-pulsed laser
  • Osseointegration
  • Osteoblast
  • Zirconia implant


Dive into the research topics of 'Cortical bone response toward nanosecond-pulsed laser-treated zirconia implant surfaces'. Together they form a unique fingerprint.

Cite this