Cortical glucose metabolism in psychiatric wandering patients with vascular dementia

Kenichi Meguro, Satoshi Yamaguchi, Hideki Yamazaki, Masatoshi Itoh, Tatsuo Yamaguchi, Hiroshige Matsui, Hidetada Sasaki

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


The cerebral metabolic rate for glucose (CMR(glc)) in 18 patients with vascular dementia (VD) and 15 age-matched normal subjects was measured with positron emission tomography (PET) and the 18F-fluorodeoxyglucose technique. Nine of the 18 VD patients manifested abnormal wandering behavior with some psychiatric symptoms: they showed relatively spared CMR(glc), which was higher than that of nonwandering patients, especially in the bilateral frontal lobes, left parietal lobe, left temporo-parieto-occipital region, left occipital lobe, and cerebellum. The results suggest that psychiatric wandering behavior of patients with VD could be correlated with partial sparing of CMR(glc) in the regions listed above.

Original languageEnglish
Pages (from-to)71-80
Number of pages10
JournalPsychiatry Research - Neuroimaging
Issue number1
Publication statusPublished - 1996 May 31


  • Aging
  • Geriatric psychiatry
  • Multi-infarct dementia
  • Positron emission tomography


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