Cortical laminar necrosis in a patient with moyamoya disease associated with Down syndrome: MR imaging findings

K. Takeda, S. Takahashi, S. Higano, N. Kurihara, K. Haginoya, R. Shirane, K. Sakamoto

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

We report a case of moyamoya disease associated with Down syndrome and congenital heart malformations. Findings of cranial MR imaging indicated cortical laminar necrosis along with cerebral infarction. To explain the development of these findings, we hypothesized that hypoxic brain damage manifesting cortical laminar necrosis was caused by hypoperfusion of the brain due to occlusive changes to the cerebral vessels in moyamoya disease, in addition to a state of general hypoxemia secondary to congenital heart malformations.

Original languageEnglish
Pages (from-to)59-63
Number of pages5
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Volume15
Issue number1
Publication statusPublished - 1997

Keywords

  • cortical laminar necrosis
  • Down syndrome
  • magnetic resonance imaging
  • moyamoya disease

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