Crystal growth on bioactive glass sputter-coated alumina in artificial saliva

Masahiro Iijima, Masanori Hashimoto, Naohisa Kohda, Susumu Nakagaki, Takeshi Muguruma, Kazuhiko Endo, Itaru Mizoguchi

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


In this work, a bioactive glass was deposited on the alumina disk specimens by radio-frequency magnetron sputtering to study crystal formation ability in artificial saliva. Bioactive glass-coated specimens were immersed in artificial saliva for 1 week and 6 months. The specimens were observed with a scanning electron microscope (SEM) and the composition was determined by energy dispersive spectroscopy (EDS). The crystals that formed on the specimens were analyzed by Raman spectroscopic analysis and Micro-X-ray diffraction. SEM photomicrographs showed the formation of needle-like structures after immersion for 1 week, and tabular structures formed on the surface of the specimen for 6 months. EDS showed that both the needle-like and tabular structures were enriched with Ca and P. Raman and Micro-XRD spectra for the tabular structure showed peaks that may correspond to calcium phosphate. Thus, when immersed in artificial saliva, bioactive glass-coated alumina produced a crystal which might be calcium phosphate.

Original languageEnglish
Pages (from-to)775-780
Number of pages6
JournalDental Materials Journal
Issue number5
Publication statusPublished - 2013


  • Alumina
  • Bioactive glass
  • Coating
  • Crystal formation
  • Remineralization


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