Cushing's disease associated with unruptured large internal carotid artery aneurysm

Yasuo Nishijima; Yoshikazu Ogawa; Kenichi Sato; Yasushi Matsumoto; Teiji Tominaga

doi:10.2176/nmc.50.665

Cushing's disease associated with unruptured large internal carotid artery aneurysm

Yasuo Nishijima, Yoshikazu Ogawa, Kenichi Sato, Yasushi Matsumoto, Teiji Tominaga

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

A 40-year-old woman with Cushing's disease presented with hypertensive cerebral hemorrhage. Neuroimaging detected an unruptured large intracavernous aneurysm, which projected beyond the midline, and thin crescent-shaped adenoma along the aneurysm wall. The aneurysm was treated with endovascular tight packing with coils. Transsphenoidal adenomectomy was then safely performed. The signs of Cushing's disease were resolved, and she was discharged without deficits. The first line therapy for Cushing's disease is transsphenoidal adenomectomy. However, the therapeutic strategy and optimal timing of treatment are unclear for Cushing's disease with large intracavernous aneurysm. The present case shows that transsphenoidal surgery was safely possible with minimal invasiveness after embolizationof the intracavernous aneurysm.

Original language	English
Pages (from-to)	665-668
Number of pages	4
Journal	Neurologia Medico-Chirurgica
Volume	50
Issue number	8
DOIs	https://doi.org/10.2176/nmc.50.665
Publication status	Published - 2010

Keywords

Cushing's disease
Embolization
Internal carotid artery aneurysm
Pituitary
Transsphenoidal surgery

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10.2176/nmc.50.665

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abstract = "A 40-year-old woman with Cushing's disease presented with hypertensive cerebral hemorrhage. Neuroimaging detected an unruptured large intracavernous aneurysm, which projected beyond the midline, and thin crescent-shaped adenoma along the aneurysm wall. The aneurysm was treated with endovascular tight packing with coils. Transsphenoidal adenomectomy was then safely performed. The signs of Cushing's disease were resolved, and she was discharged without deficits. The first line therapy for Cushing's disease is transsphenoidal adenomectomy. However, the therapeutic strategy and optimal timing of treatment are unclear for Cushing's disease with large intracavernous aneurysm. The present case shows that transsphenoidal surgery was safely possible with minimal invasiveness after embolizationof the intracavernous aneurysm.",

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T1 - Cushing's disease associated with unruptured large internal carotid artery aneurysm

AU - Nishijima, Yasuo

AU - Ogawa, Yoshikazu

AU - Sato, Kenichi

AU - Matsumoto, Yasushi

AU - Tominaga, Teiji

PY - 2010

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N2 - A 40-year-old woman with Cushing's disease presented with hypertensive cerebral hemorrhage. Neuroimaging detected an unruptured large intracavernous aneurysm, which projected beyond the midline, and thin crescent-shaped adenoma along the aneurysm wall. The aneurysm was treated with endovascular tight packing with coils. Transsphenoidal adenomectomy was then safely performed. The signs of Cushing's disease were resolved, and she was discharged without deficits. The first line therapy for Cushing's disease is transsphenoidal adenomectomy. However, the therapeutic strategy and optimal timing of treatment are unclear for Cushing's disease with large intracavernous aneurysm. The present case shows that transsphenoidal surgery was safely possible with minimal invasiveness after embolizationof the intracavernous aneurysm.

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KW - Cushing's disease

KW - Embolization

KW - Internal carotid artery aneurysm

KW - Pituitary

KW - Transsphenoidal surgery

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Cushing's disease associated with unruptured large internal carotid artery aneurysm

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Keywords

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