Cyanohydrin Alkylation Approach To A Chiral A-Ring Synthon For 1α,25-Dihydroxyvitamin D3

Takashi Takahashi; Takayuki Doi; Makoto Nakazawa; Haruo Yamada

doi:10.1080/10575639308050064

Cyanohydrin Alkylation Approach To A Chiral A-Ring Synthon For 1α,25-Dihydroxyvitamin D3

Takashi Takahashi, Takayuki Doi, Makoto Nakazawa, Haruo Yamada

Research output: Contribution to journal › Article › peer-review

Abstract

We report here the synthesis of a chiral A-ring synthon for la, 25-dihydroxyvitamin D3 starting from d-mannitol by using the cyanohydrin cyclization methodology.

Original language	English
Pages (from-to)	299-304
Number of pages	6
Journal	Natural Product Letters
Volume	1
Issue number	4
DOIs	https://doi.org/10.1080/10575639308050064
Publication status	Published - 1993 Feb 1
Externally published	Yes

Keywords

1α
25-dihydroxyvitamin D3
A-ring synthon
cyanohydrin alkylation
d-mannitol

ASJC Scopus subject areas

Molecular Medicine

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10.1080/10575639308050064

Cite this

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title = "Cyanohydrin Alkylation Approach To A Chiral A-Ring Synthon For 1α,25-Dihydroxyvitamin D3",

abstract = "We report here the synthesis of a chiral A-ring synthon for la, 25-dihydroxyvitamin D3 starting from d-mannitol by using the cyanohydrin cyclization methodology.",

keywords = "1α, 25-dihydroxyvitamin D3, A-ring synthon, cyanohydrin alkylation, d-mannitol",

author = "Takashi Takahashi and Takayuki Doi and Makoto Nakazawa and Haruo Yamada",

year = "1993",

month = feb,

day = "1",

doi = "10.1080/10575639308050064",

language = "English",

volume = "1",

pages = "299--304",

journal = "Natural Product Research",

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T1 - Cyanohydrin Alkylation Approach To A Chiral A-Ring Synthon For 1α,25-Dihydroxyvitamin D3

AU - Takahashi, Takashi

AU - Doi, Takayuki

AU - Nakazawa, Makoto

AU - Yamada, Haruo

PY - 1993/2/1

Y1 - 1993/2/1

N2 - We report here the synthesis of a chiral A-ring synthon for la, 25-dihydroxyvitamin D3 starting from d-mannitol by using the cyanohydrin cyclization methodology.

AB - We report here the synthesis of a chiral A-ring synthon for la, 25-dihydroxyvitamin D3 starting from d-mannitol by using the cyanohydrin cyclization methodology.

KW - 1α

KW - 25-dihydroxyvitamin D3

KW - A-ring synthon

KW - cyanohydrin alkylation

KW - d-mannitol

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VL - 1

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ER -

Cyanohydrin Alkylation Approach To A Chiral A-Ring Synthon For 1α,25-Dihydroxyvitamin D3

Abstract

Keywords

ASJC Scopus subject areas

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