Degradation of β-hexachlorocyclohexane by haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26

Yuji Nagata, Zbyněk Prokop, Yukari Sato, Petr Jerabek, Ashwani Kumar, Yoshiyuki Ohtsubo, Masataka Tsuda, Jiří Damborský

Research output: Contribution to journalArticlepeer-review

63 Citations (Scopus)

Abstract

β-Hexachlorocyclohexane (β-HCH) is the most recalcitrant among the α-, β-, γ-, and δ-isomers of HCH and causes serious environmental pollution problems. We demonstrate here that the haloalkane dehalogenase LinB, reported earlier to mediate the second step in the degradation of γ-HCH in Sphingomonas paucimobilis UT26, metabolizes β-HCH to produce 2,3,4,5,6-pentachlorocyclohexanol.

Original languageEnglish
Pages (from-to)2183-2185
Number of pages3
JournalApplied and Environmental Microbiology
Volume71
Issue number4
DOIs
Publication statusPublished - 2005 Apr

Fingerprint

Dive into the research topics of 'Degradation of β-hexachlorocyclohexane by haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26'. Together they form a unique fingerprint.

Cite this