Design and Synthesis of b-Series Ganglioside Mimetics

Tsuyoshi Miura; Mitsuaki Aonuma; Telsuya Kajimoto; Yoshiteru Ida; Mitsuo Kawase; Yuji Kawase; Yasuko Yoshida

doi:10.1055/s-1997-3259

Design and Synthesis of b-Series Ganglioside Mimetics

Tsuyoshi Miura, Mitsuaki Aonuma, Telsuya Kajimoto, Yoshiteru Ida, Mitsuo Kawase, Yuji Kawase, Yasuko Yoshida

MEN - Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Artificial glycolipids composed from phosphatidyl-ethanolamine and one or two sets of sialylα(2-8)sialoside were designed and prepared as mimetics of b-series gangliosides, GD₃ and GQ_1b, which have respectively cholinergic differentiation potency in murine neuroblastoma cells and neutritogenic effect in human neuroblastoma cell line.

Original language	English
Pages (from-to)	650-652
Number of pages	3
Journal	Synlett
Volume	1997
Issue number	6
DOIs	https://doi.org/10.1055/s-1997-3259
Publication status	Published - 1997

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10.1055/s-1997-3259

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abstract = "Artificial glycolipids composed from phosphatidyl-ethanolamine and one or two sets of sialylα(2-8)sialoside were designed and prepared as mimetics of b-series gangliosides, GD3 and GQ1b, which have respectively cholinergic differentiation potency in murine neuroblastoma cells and neutritogenic effect in human neuroblastoma cell line.",

author = "Tsuyoshi Miura and Mitsuaki Aonuma and Telsuya Kajimoto and Yoshiteru Ida and Mitsuo Kawase and Yuji Kawase and Yasuko Yoshida",

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AU - Miura, Tsuyoshi

AU - Aonuma, Mitsuaki

AU - Kajimoto, Telsuya

AU - Ida, Yoshiteru

AU - Kawase, Mitsuo

AU - Kawase, Yuji

AU - Yoshida, Yasuko

PY - 1997

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N2 - Artificial glycolipids composed from phosphatidyl-ethanolamine and one or two sets of sialylα(2-8)sialoside were designed and prepared as mimetics of b-series gangliosides, GD3 and GQ1b, which have respectively cholinergic differentiation potency in murine neuroblastoma cells and neutritogenic effect in human neuroblastoma cell line.

AB - Artificial glycolipids composed from phosphatidyl-ethanolamine and one or two sets of sialylα(2-8)sialoside were designed and prepared as mimetics of b-series gangliosides, GD3 and GQ1b, which have respectively cholinergic differentiation potency in murine neuroblastoma cells and neutritogenic effect in human neuroblastoma cell line.

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DO - 10.1055/s-1997-3259

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VL - 1997

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EP - 652

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JF - Synlett

IS - 6

ER -

Design and Synthesis of b-Series Ganglioside Mimetics

Abstract

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