We demonstrate a metal-organic framework (MOF) design for the inclusion of hydroxide ions. Salt inclusion method was applied to an alkaline-stable ZIF-8 (ZIF = zeolitic imidazolate framework) to introduce alkylammonium hydroxides as ionic carriers. We found that tetrabutylammonium salts are immobilized inside the pores by a hydrophobic interaction between the alkyl groups of the salt and the framework, which significantly increases the hydrophilicity of ZIF-8. Furthermore, ZIF-8 including the salt exhibited a capacity for OH- ion exchange, implying that freely exchangeable OH- ions are present in the MOF. ZIF-8 containing OH- ions showed an ionic conductivity of 2.3 × 10-8 S cm-1 at 25 C, which is 4 orders of magnitude higher than that of the blank ZIF-8. This is the first example of an MOF-based hydroxide ion conductor.