TY - JOUR
T1 - Design and testing of a W-MoO3 target system for electron linac production of 99Mo/99mTc
AU - Jang, Jaewoong
AU - Kikunaga, Hidetoshi
AU - Sekimoto, Shun
AU - Inagaki, Makoto
AU - Kawakami, Tomohiko
AU - Ohtsuki, Tsutomu
AU - Kashiwagi, Shigeru
AU - Takahashi, Ken
AU - Tsukada, Kyo
AU - Tatenuma, Katsuyoshi
AU - Uesaka, Mitsuru
N1 - Funding Information:
This work was supported by the joint research program of ELPH, Tohoku University (Nos. 2914 and 2921), by Japan Society for the Promotion of Science through Grants-in-Aid for Scientific Research (Nos. 19K22596 , 18H04150 , and 16K15579 to TO, and 19K21993 , 18H01312 , and 16K15580 to SS), and by Kansai Genshiryoku Kondankai (to TO and SS).
Funding Information:
This work was supported by the joint research program of ELPH, Tohoku University (Nos. 2914 and 2921), by Japan Society for the Promotion of Science through Grants-in-Aid for Scientific Research (Nos. 19K22596, 18H04150, and 16K15579 to TO, and 19K21993, 18H01312, and 16K15580 to SS), and by Kansai Genshiryoku Kondankai (to TO and SS). This paper contains part of a dissertation submitted by JJ to the University of Tokyo [22], and part of a study conducted within the Coordinated Research Project on ?New Ways of Producing Tc-99m and Tc-99m Generators (F22068)?, implemented by the International Atomic Energy Agency. Experimental assistance from Y. Inoue (University of Tokyo) and advice on MoO3 sintering from Y. Natori (Kaken Inc.) are appreciated.
Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2021/1/21
Y1 - 2021/1/21
N2 - To improve the efficiency of electron linear accelerator production of 99Mo/99mTc, a W-MoO3 target system was designed and its 99Mo production performance was tested. Irradiation experiments were carried out for sets of electron beam energies and W thicknesses, which were then compared with Monte Carlo simulations. Optimal W thicknesses of the target system were found to be 1.5mm, 2.5mm, and 3.0mm for electron beams of 22.2MeV, 38.9MeV, and 55.5MeV, respectively. The use of these W thicknesses can improve the 99Mo production performance, and the use of MoO3 targets can facilitate postirradiation processing.
AB - To improve the efficiency of electron linear accelerator production of 99Mo/99mTc, a W-MoO3 target system was designed and its 99Mo production performance was tested. Irradiation experiments were carried out for sets of electron beam energies and W thicknesses, which were then compared with Monte Carlo simulations. Optimal W thicknesses of the target system were found to be 1.5mm, 2.5mm, and 3.0mm for electron beams of 22.2MeV, 38.9MeV, and 55.5MeV, respectively. The use of these W thicknesses can improve the 99Mo production performance, and the use of MoO3 targets can facilitate postirradiation processing.
KW - Mo/Tc
KW - Electron linear accelerator
KW - Nuclear medicine
KW - Targetry
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U2 - 10.1016/j.nima.2020.164815
DO - 10.1016/j.nima.2020.164815
M3 - Article
AN - SCOPUS:85095431881
SN - 0168-9002
VL - 987
JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
M1 - 164815
ER -