If the multiple‐valued digital system can be extended to an ultrahigher‐valued digital system, the potential advantages of high information density and simple hardware algorithms by direct multiple‐valued coding of the processed data will be obtained. This paper presents a highly parallel ultra‐higher‐valued logic network composed of bio‐devices based on specificity of enzymes, i.e., the high‐level, multiple‐valued discrimination function. First, the multiple‐valued coding of varieties of organic molecules is presented, regarding the molecules as logic values. Then, basic bio‐devices are defined which can switch the molecular logic values. It is shown that any multiple‐valued logic function can be constructed in two‐stage structure by the proposed bio‐devices. Finally, the systematic synthesis method of the network is presented aiming at the minimization of the network. Since one of the most distinctive features of the proposed system is that there is no physical order relation among the logic values, the simplification of logic networks without a constraint due to the adjacency of the logic values is discussed anew.