Development of a GSO detector assembly for a continuous blood sampling system

Nobuyuki Kudomi; Eunjoo Choi; Seiichi Yamamoto; Hiroshi Watabe; Kyeong Min Kim; Miho Shidahara; Mikako Ogawa; Noboru Teramoto; Eishi Sakamoto; Hidehiro Iida

doi:10.1109/TNS.2002.807869

Development of a GSO detector assembly for a continuous blood sampling system

Nobuyuki Kudomi, Eunjoo Choi, Seiichi Yamamoto, Hiroshi Watabe, Kyeong Min Kim, Miho Shidahara, Mikako Ogawa, Noboru Teramoto, Eishi Sakamoto, Hidehiro Iida

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

A new input function monitoring system has been developed and evaluated using a GSO detector assembly for both PET and SPECT quantitative studies. Energy resolutions were 11% for 511 kev photons, 20% for 140 keV(^99mTc) photons and 28% for 70 keV(²⁰¹Tl) photons, enabling the use of this system in SPECT studies. The paired assembly of crystals provided an absolute sensitivity of approximately 7% for PET tracers and 70% for ^99mTc and ²⁰¹Tl (SPECT tracers). Multiple arrangement of paired detectors would make it possible to correct for the transit time of radioactivity through the catheter tube. This study demonstrates that the present system can be of use in both clinical and small animal studies using SPECT and PET tracers.

Original language	English
Pages (from-to)	70-73
Number of pages	4
Journal	IEEE Transactions on Nuclear Science
Volume	50 I
Issue number	1
DOIs	https://doi.org/10.1109/TNS.2002.807869
Publication status	Published - 2003 Feb

Keywords

Arterial input function monitor
Positron emission tomography (PET)
Single photon emission tomography

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10.1109/TNS.2002.807869

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title = "Development of a GSO detector assembly for a continuous blood sampling system",

abstract = "A new input function monitoring system has been developed and evaluated using a GSO detector assembly for both PET and SPECT quantitative studies. Energy resolutions were 11% for 511 kev photons, 20% for 140 keV(99mTc) photons and 28% for 70 keV(201Tl) photons, enabling the use of this system in SPECT studies. The paired assembly of crystals provided an absolute sensitivity of approximately 7% for PET tracers and 70% for 99mTc and 201Tl (SPECT tracers). Multiple arrangement of paired detectors would make it possible to correct for the transit time of radioactivity through the catheter tube. This study demonstrates that the present system can be of use in both clinical and small animal studies using SPECT and PET tracers.",

keywords = "Arterial input function monitor, Positron emission tomography (PET), Single photon emission tomography",

author = "Nobuyuki Kudomi and Eunjoo Choi and Seiichi Yamamoto and Hiroshi Watabe and Kim, {Kyeong Min} and Miho Shidahara and Mikako Ogawa and Noboru Teramoto and Eishi Sakamoto and Hidehiro Iida",

note = "Funding Information: Manuscript received November 25, 2001; revised August 9, 2002. This work was supported by the Program for Promotion of Fundamental Studies in Health Science of the Organization for Pharmaceutical Safety and Research of Japan and by the Japanese Cardiovascular Research Foundation.",

year = "2003",

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doi = "10.1109/TNS.2002.807869",

language = "English",

volume = "50 I",

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AU - Kudomi, Nobuyuki

AU - Choi, Eunjoo

AU - Yamamoto, Seiichi

AU - Watabe, Hiroshi

AU - Kim, Kyeong Min

AU - Shidahara, Miho

AU - Ogawa, Mikako

AU - Teramoto, Noboru

AU - Sakamoto, Eishi

AU - Iida, Hidehiro

N1 - Funding Information: Manuscript received November 25, 2001; revised August 9, 2002. This work was supported by the Program for Promotion of Fundamental Studies in Health Science of the Organization for Pharmaceutical Safety and Research of Japan and by the Japanese Cardiovascular Research Foundation.

PY - 2003/2

Y1 - 2003/2

N2 - A new input function monitoring system has been developed and evaluated using a GSO detector assembly for both PET and SPECT quantitative studies. Energy resolutions were 11% for 511 kev photons, 20% for 140 keV(99mTc) photons and 28% for 70 keV(201Tl) photons, enabling the use of this system in SPECT studies. The paired assembly of crystals provided an absolute sensitivity of approximately 7% for PET tracers and 70% for 99mTc and 201Tl (SPECT tracers). Multiple arrangement of paired detectors would make it possible to correct for the transit time of radioactivity through the catheter tube. This study demonstrates that the present system can be of use in both clinical and small animal studies using SPECT and PET tracers.

AB - A new input function monitoring system has been developed and evaluated using a GSO detector assembly for both PET and SPECT quantitative studies. Energy resolutions were 11% for 511 kev photons, 20% for 140 keV(99mTc) photons and 28% for 70 keV(201Tl) photons, enabling the use of this system in SPECT studies. The paired assembly of crystals provided an absolute sensitivity of approximately 7% for PET tracers and 70% for 99mTc and 201Tl (SPECT tracers). Multiple arrangement of paired detectors would make it possible to correct for the transit time of radioactivity through the catheter tube. This study demonstrates that the present system can be of use in both clinical and small animal studies using SPECT and PET tracers.

KW - Arterial input function monitor

KW - Positron emission tomography (PET)

KW - Single photon emission tomography

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Development of a GSO detector assembly for a continuous blood sampling system

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