TY - JOUR
T1 - Development of a new statistical evaluation method for Brain SPECT images
AU - Kawashima, Ryuta
AU - Sato, Kazunori
AU - Ito, Hiroshi
AU - Koyama, Masamichi
AU - Goto, Ryoui
AU - Yoshioka, Seiro
AU - Ono, Shuichi
AU - Sato, Tachio
AU - Fukuda, Hiroshi
PY - 1996
Y1 - 1996
N2 - The purpose of this study was to develop a new statistical evaluation method for Brain SPECT images. First, we made normal brain image databases using 99mTc-ECD and SPECT in 10 normal subjects as described previously. Each SPECT images were globally normalized and anatomically standardized to the standard brain shape using Human Brain Atlas (HBA) of Roland et al. and each subject's X-CT. Then, mean and SD images were calculated voxel by voxel. For the next step, 99mTc-ECD SPECT images of a patient were obtained, and global normalization and anatomical standardization were performed as the same way. Then, a statistical map was calculated as following voxel by voxel; (P - Mean)/SD x 10 + 50, where P, Mean and SD indicate voxel value of patient, mean and SD images of normal databases, respectively. We found this statistical map was helpful for clinical diagnosis of brain SPECT studies.
AB - The purpose of this study was to develop a new statistical evaluation method for Brain SPECT images. First, we made normal brain image databases using 99mTc-ECD and SPECT in 10 normal subjects as described previously. Each SPECT images were globally normalized and anatomically standardized to the standard brain shape using Human Brain Atlas (HBA) of Roland et al. and each subject's X-CT. Then, mean and SD images were calculated voxel by voxel. For the next step, 99mTc-ECD SPECT images of a patient were obtained, and global normalization and anatomical standardization were performed as the same way. Then, a statistical map was calculated as following voxel by voxel; (P - Mean)/SD x 10 + 50, where P, Mean and SD indicate voxel value of patient, mean and SD images of normal databases, respectively. We found this statistical map was helpful for clinical diagnosis of brain SPECT studies.
KW - Anatomical standardization
KW - Cerebral blood flow
KW - Human brain
KW - Normal database
KW - SPECT
KW - Statistical image
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M3 - Article
C2 - 9023443
AN - SCOPUS:0030445411
SN - 0022-7854
VL - 33
SP - 1359
EP - 1362
JO - Kaku igaku. The Japanese journal of nuclear medicine
JF - Kaku igaku. The Japanese journal of nuclear medicine
IS - 12
ER -
