Development of a novel hypoxia maker; [ 18F]FRP-170, and its initial clinical application for tumor imaging

Yoshihiro Takai; E. Nakata; T. Kaneta; T. Hamatsuka; S. Yamada; Ren Iwata; Y. Funaki; Y. Ishikawa; N. Tsujitani

Development of a novel hypoxia maker; [ ¹⁸F]FRP-170, and its initial clinical application for tumor imaging

Yoshihiro Takai, E. Nakata, T. Kaneta, T. Hamatsuka, S. Yamada, Ren Iwata, Y. Funaki, Y. Ishikawa, N. Tsujitani

Research output: Contribution to journal › Article › peer-review

Abstract

In clinical study, tumor/muscle ratios from 12 sites of 8 patients evaluated by PET were 0.8-2.14, and average ratio except for radiosensitive malignant lymphoma (1.07) and small cell lung cancer (1.0) was 1.58. Because of low lipophilicity of the tracer, the background activities decreased rapidly. We conclude from these data that [ ¹⁸F]FRP-170 is a promising new hypoxia marker in cancer patients.

Original language	English
Pages (from-to)	837-843
Number of pages	7
Journal	Japanese Journal of Clinical Radiology
Volume	51
Issue number	7
Publication status	Published - 2006 Aug 15

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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abstract = "In clinical study, tumor/muscle ratios from 12 sites of 8 patients evaluated by PET were 0.8-2.14, and average ratio except for radiosensitive malignant lymphoma (1.07) and small cell lung cancer (1.0) was 1.58. Because of low lipophilicity of the tracer, the background activities decreased rapidly. We conclude from these data that [ 18F]FRP-170 is a promising new hypoxia marker in cancer patients.",

author = "Yoshihiro Takai and E. Nakata and T. Kaneta and T. Hamatsuka and S. Yamada and Ren Iwata and Y. Funaki and Y. Ishikawa and N. Tsujitani",

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T1 - Development of a novel hypoxia maker; [ 18F]FRP-170, and its initial clinical application for tumor imaging

AU - Takai, Yoshihiro

AU - Nakata, E.

AU - Kaneta, T.

AU - Hamatsuka, T.

AU - Yamada, S.

AU - Iwata, Ren

AU - Funaki, Y.

AU - Ishikawa, Y.

AU - Tsujitani, N.

PY - 2006/8/15

Y1 - 2006/8/15

N2 - In clinical study, tumor/muscle ratios from 12 sites of 8 patients evaluated by PET were 0.8-2.14, and average ratio except for radiosensitive malignant lymphoma (1.07) and small cell lung cancer (1.0) was 1.58. Because of low lipophilicity of the tracer, the background activities decreased rapidly. We conclude from these data that [ 18F]FRP-170 is a promising new hypoxia marker in cancer patients.

AB - In clinical study, tumor/muscle ratios from 12 sites of 8 patients evaluated by PET were 0.8-2.14, and average ratio except for radiosensitive malignant lymphoma (1.07) and small cell lung cancer (1.0) was 1.58. Because of low lipophilicity of the tracer, the background activities decreased rapidly. We conclude from these data that [ 18F]FRP-170 is a promising new hypoxia marker in cancer patients.

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ER -

Development of a novel hypoxia maker; [ ¹⁸F]FRP-170, and its initial clinical application for tumor imaging

Abstract

ASJC Scopus subject areas

UN SDGs

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