Development of a practical image-based scatter correction method for brain perfusion SPECT: Comparison with the TEW method

Miho Shidahara; Hiroshi Watabe; Min Kim Kyeong; Takashi Kato; Shoji Kawatsu; Rikio Kato; Kumiko Yoshimura; Hidehiro Iida; Kengo Ito

doi:10.1007/s00259-005-1791-2

Development of a practical image-based scatter correction method for brain perfusion SPECT: Comparison with the TEW method

Miho Shidahara, Hiroshi Watabe, Min Kim Kyeong, Takashi Kato, Shoji Kawatsu, Rikio Kato, Kumiko Yoshimura, Hidehiro Iida, Kengo Ito

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Purpose: An image-based scatter correction (IBSC) method was developed to convert scatter-uncorrected into scatter-corrected SPECT images. The purpose of this study was to validate this method by means of phantom simulations and human studies with ^99mTc-labeled tracers, based on comparison with the conventional triple energy window (TEW) method. Methods: The IBSC method corrects scatter on the reconstructed image I_AC^μb with Chang's attenuation correction factor. The scatter component image is estimated by convolving I_AC^μb with a scatter function followed by multiplication with an image-based scatter fraction function. The IBSC method was evaluated with Monte Carlo simulations and ^99mTc-ethyl cysteinate dimer SPECT human brain perfusion studies obtained from five volunteers. The image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were compared. Results: Using data obtained from the simulations, the image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were found to be nearly identical for both gray and white matter. In human brain images, no significant differences in image contrast were observed between the IBSC and TEW methods. Conclusion: The IBSC method is a simple scatter correction technique feasible for use in clinical routine.

Original language	English
Pages (from-to)	1193-1198
Number of pages	6
Journal	European Journal of Nuclear Medicine and Molecular Imaging
Volume	32
Issue number	10
DOIs	https://doi.org/10.1007/s00259-005-1791-2
Publication status	Published - 2005 Oct

Keywords

Attenuation correction
Cerebral perfusion
Image conversion
Scatter correction
Single-photon emission tomography

Access to Document

10.1007/s00259-005-1791-2

Cite this

@article{3c1b6a271d5245dbbf13bb60f8e08629,

title = "Development of a practical image-based scatter correction method for brain perfusion SPECT: Comparison with the TEW method",

abstract = "Purpose: An image-based scatter correction (IBSC) method was developed to convert scatter-uncorrected into scatter-corrected SPECT images. The purpose of this study was to validate this method by means of phantom simulations and human studies with 99mTc-labeled tracers, based on comparison with the conventional triple energy window (TEW) method. Methods: The IBSC method corrects scatter on the reconstructed image IACμb with Chang's attenuation correction factor. The scatter component image is estimated by convolving IACμb with a scatter function followed by multiplication with an image-based scatter fraction function. The IBSC method was evaluated with Monte Carlo simulations and 99mTc-ethyl cysteinate dimer SPECT human brain perfusion studies obtained from five volunteers. The image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were compared. Results: Using data obtained from the simulations, the image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were found to be nearly identical for both gray and white matter. In human brain images, no significant differences in image contrast were observed between the IBSC and TEW methods. Conclusion: The IBSC method is a simple scatter correction technique feasible for use in clinical routine.",

keywords = "Attenuation correction, Cerebral perfusion, Image conversion, Scatter correction, Single-photon emission tomography",

author = "Miho Shidahara and Hiroshi Watabe and Kyeong, {Min Kim} and Takashi Kato and Shoji Kawatsu and Rikio Kato and Kumiko Yoshimura and Hidehiro Iida and Kengo Ito",

note = "Funding Information: Acknowledgements. This work was supported in part by a Grant-in-Aid for Science Research of The Ministry of Education, Culture, Sports, Science and Technology, research grant 1420061.",

year = "2005",

month = oct,

doi = "10.1007/s00259-005-1791-2",

language = "English",

volume = "32",

pages = "1193--1198",

journal = "European Journal of Nuclear Medicine and Molecular Imaging",

issn = "1619-7070",

publisher = "Springer Verlag",

number = "10",

}

TY - JOUR

T1 - Development of a practical image-based scatter correction method for brain perfusion SPECT

T2 - Comparison with the TEW method

AU - Shidahara, Miho

AU - Watabe, Hiroshi

AU - Kyeong, Min Kim

AU - Kato, Takashi

AU - Kawatsu, Shoji

AU - Kato, Rikio

AU - Yoshimura, Kumiko

AU - Iida, Hidehiro

AU - Ito, Kengo

N1 - Funding Information: Acknowledgements. This work was supported in part by a Grant-in-Aid for Science Research of The Ministry of Education, Culture, Sports, Science and Technology, research grant 1420061.

PY - 2005/10

Y1 - 2005/10

N2 - Purpose: An image-based scatter correction (IBSC) method was developed to convert scatter-uncorrected into scatter-corrected SPECT images. The purpose of this study was to validate this method by means of phantom simulations and human studies with 99mTc-labeled tracers, based on comparison with the conventional triple energy window (TEW) method. Methods: The IBSC method corrects scatter on the reconstructed image IACμb with Chang's attenuation correction factor. The scatter component image is estimated by convolving IACμb with a scatter function followed by multiplication with an image-based scatter fraction function. The IBSC method was evaluated with Monte Carlo simulations and 99mTc-ethyl cysteinate dimer SPECT human brain perfusion studies obtained from five volunteers. The image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were compared. Results: Using data obtained from the simulations, the image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were found to be nearly identical for both gray and white matter. In human brain images, no significant differences in image contrast were observed between the IBSC and TEW methods. Conclusion: The IBSC method is a simple scatter correction technique feasible for use in clinical routine.

AB - Purpose: An image-based scatter correction (IBSC) method was developed to convert scatter-uncorrected into scatter-corrected SPECT images. The purpose of this study was to validate this method by means of phantom simulations and human studies with 99mTc-labeled tracers, based on comparison with the conventional triple energy window (TEW) method. Methods: The IBSC method corrects scatter on the reconstructed image IACμb with Chang's attenuation correction factor. The scatter component image is estimated by convolving IACμb with a scatter function followed by multiplication with an image-based scatter fraction function. The IBSC method was evaluated with Monte Carlo simulations and 99mTc-ethyl cysteinate dimer SPECT human brain perfusion studies obtained from five volunteers. The image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were compared. Results: Using data obtained from the simulations, the image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were found to be nearly identical for both gray and white matter. In human brain images, no significant differences in image contrast were observed between the IBSC and TEW methods. Conclusion: The IBSC method is a simple scatter correction technique feasible for use in clinical routine.

KW - Attenuation correction

KW - Cerebral perfusion

KW - Image conversion

KW - Scatter correction

KW - Single-photon emission tomography

UR - http://www.scopus.com/inward/record.url?scp=25144502369&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=25144502369&partnerID=8YFLogxK

U2 - 10.1007/s00259-005-1791-2

DO - 10.1007/s00259-005-1791-2

M3 - Article

C2 - 15924230

AN - SCOPUS:25144502369

SN - 1619-7070

VL - 32

SP - 1193

EP - 1198

JO - European Journal of Nuclear Medicine and Molecular Imaging

JF - European Journal of Nuclear Medicine and Molecular Imaging

IS - 10

ER -

Development of a practical image-based scatter correction method for brain perfusion SPECT: Comparison with the TEW method

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this