TY - GEN
T1 - Development of autonomic regulation model for cardiovascular system simulations
AU - Goto, Tomonobu
AU - Sakamoto, Hiroto
AU - Utsunomiya, Atsushi
AU - Shishikura, Kenta
N1 - Funding Information:
This work was supported by JSPS KAKENHI (JP16H04460, JP20H02307).
Publisher Copyright:
© 2020 16th Conference of the International Society of Indoor Air Quality and Climate: Creative and Smart Solutions for Better Built Environments, Indoor Air 2020. All rights reserved.
PY - 2020
Y1 - 2020
N2 - In order to evaluate health risks under sever thermal environments, we are developing a new human model that can predict BP and BFR, as well as body temperature. In this study, we developed one of the sub-models for our human model, i.e. autonomic regulation model, which predicts human responses on vasomotor and cardiac activities for thermoregulation and baroreflex. We also conducted some simulations by using the autonomic regulation model combined with our previously developed model of cardiovascular system. The results showed that the simulations reproduced reasonably the actual BP and BFR under four different thermal and postural conditions, i.e. 18°C, 28°C, 40°C-supine and 28°C-standing. Only in the 18°C-supine case, there was a substantial problem on the BP simulation, however, it will be solved by the incorporation of more precise vasomotor activity.
AB - In order to evaluate health risks under sever thermal environments, we are developing a new human model that can predict BP and BFR, as well as body temperature. In this study, we developed one of the sub-models for our human model, i.e. autonomic regulation model, which predicts human responses on vasomotor and cardiac activities for thermoregulation and baroreflex. We also conducted some simulations by using the autonomic regulation model combined with our previously developed model of cardiovascular system. The results showed that the simulations reproduced reasonably the actual BP and BFR under four different thermal and postural conditions, i.e. 18°C, 28°C, 40°C-supine and 28°C-standing. Only in the 18°C-supine case, there was a substantial problem on the BP simulation, however, it will be solved by the incorporation of more precise vasomotor activity.
KW - Blood flow rate
KW - Blood pressure
KW - Health risk
KW - Human model
KW - Thermal environment
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UR - http://www.scopus.com/inward/citedby.url?scp=85101657183&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85101657183
T3 - 16th Conference of the International Society of Indoor Air Quality and Climate: Creative and Smart Solutions for Better Built Environments, Indoor Air 2020
BT - 16th Conference of the International Society of Indoor Air Quality and Climate
PB - International Society of Indoor Air Quality and Climate
T2 - 16th Conference of the International Society of Indoor Air Quality and Climate: Creative and Smart Solutions for Better Built Environments, Indoor Air 2020
Y2 - 1 November 2020
ER -
