Development of Dual Ion-selective Electrodes in Double-Barrel Glass Pipette at One Micrometer for Simultaneous Measurement of Sodium and Potassium Ions

Tomohide Takami, Yusuke Akutsu, Naoki Kaneko, Rio Yoneda, Hideyuki Magara, Shuichi Ogawa, Tadashi Abukawa

Research output: Contribution to journalArticlepeer-review

Abstract

We have developed the method of preparing sodium and potassium ion-selective electrodes in double-barrel glass pipettes at the size of 1 μm. Stable and precise fabrication parameters were found for producing a double-barrel 1 μm pipette, and the produced double-barrel micropipettes were used in this study. The ionophores comprising of crown ethers of 12-crown-4 for sodium ions and 15-crown-5 for potassium ions were respectively doped in poly(vinyl chloride) films in the divided double-barrel glass pipette. The obtained selectivity coefficients and selectivity ratios are compared with the previous studies. The developed ion-selective dual-micropipettes can be applied for local ion-selective measurements such as living cells.

Original languageEnglish
Pages (from-to)17-23
Number of pages7
Journale-Journal of Surface Science and Nanotechnology
Volume21
Issue number1
DOIs
Publication statusPublished - 2023

Keywords

  • Double-barrel pipette
  • Ion-selective electrode
  • Micropipette
  • Potassium ion
  • Sodium ion

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