Development of Japanese version of the UCLA Prostate Cancer Index: A pilot validation study

Y. Kakehi, T. Kamoto, O. Ogawa, Y. Arai, M. S. Litwin, Y. Suzukamo, S. Fukuhara

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78 Citations (Scopus)


Background. There are tew reliable and valid instruments for measuring disease-specific health-related quality of life (HRQOL) in Japanese patients with localized prostate cancer. We developed a Japanese version of the University of California, Los Angeles Prostate Cancer Index (UCLA PCI) to assess HRQOL in Japanese patients treated with various modalities. Methods. The Japanese version (version 1.2) of the UCLA PCI was developed through a process of translation, backtranslation, and refinement after interviewing patients. Reliability and validity were examined for 125 Japanese patients with localized prostate cancer. The patients simultaneously responded to the Japanese version of the RAND 36-Item Health Survey (SF-36) and five representative questions from the International Index of Erectile Function (IIEF). Results. Internal consistency reliability was very high for both urinary and sexual function scales, and lower for bowel function. The test-retest reliability of the urinary and sexual function scales and the urinary bother scales was stable, while that of the bowel function and bother scales was relatively unstable. Sexual function scores did not correlate highly with sexual bother scores. Furthermore, poor sexual function and bother had little association with the SF-36 scores. Missing data as to urinary and bowel function/bother scales were minimal (0.8%-2.4%), while those for sexual function and bother were relatively high (4.8%-11.2%). Conclusions. The results of this pilot study, together with the previous American study, suggest ethnic or cultural difference in how impaired sexual function is integrated into overall QOL. A future cross-cultural comparative study using the UCLA PCI and SF-36 will provide useful information about the influence of cultural or ethnic differences on health-related QOL in prostate cancer patients.

Original languageEnglish
Pages (from-to)306-311
Number of pages6
JournalInternational Journal of Clinical Oncology
Issue number5
Publication statusPublished - 2002 Oct


  • Ethnic differences
  • Prostate cancer
  • Quality of life


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