@inproceedings{3f23413816f346ed9b3909f2a467adac,
title = "Development of laboratory-based x-ray phase tomographic microscope",
abstract = "Quantitative measurements of the phase shift of X-rays passing through a matter allow us to perform X-ray phase tomography for visualization of soft materials. Combination of an X-ray microscope and a grating interferometer is a promising approach to realize quantitative phase measurements with a microscopic spatial resolution. A Lau interferometer consisting of a source grating and a phase grating is available for this purpose with an incoherent laboratory X-ray source. We installed a Lau interferometer into a laboratory-based X-ray microscope adopting a copper rotating anode source and Fresnel zone plates (ZEISS Xradia 800 Ultra). A {"}twin-phase image{"}, which consists of positive and negative phase images overlaid with a certain separation, is generated through a fringe-scanning measurement with this microscope. A step for generating a quantitative phase image from the twin phase image should be developed to perform phase tomography. However, conventional deconvolution operations are not suitable because of artifacts and noise remained in resultant phase images. To reduce the artifacts and noise, an iterative calculation algorithm has been developed. The evaluation of the algorithm shows that the artifacts and noise are suppressed and quantitative phase images are obtained. Finally, results of phase tomography obtained for soft materials are demonstrated.",
keywords = "Grating interferometry, Laboratory source, Phase contrast, X-ray microscopy",
author = "H. Takano and K. Hashimoto and Y. Nagatani and Y. Wu and A. Momose",
note = "Funding Information: This work was supported by JST-ERATO (grant No. JPMJER1403), Japan. The authors thank Carl Zeiss X-Ray Microscopy Inc. (Pleasanton, CA, USA) for help in installing the grating interferometer into the ZEISS Xradia 800 Ultra X-ray microscope. The larva of Ciona intestinalis was prepared and provided by Prof. Kohichi Matsuo and Dr. Kohji Hotta at Keio University, Japan. Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; 12th SPIE Conference on Developments in X-Ray Tomography 2019 ; Conference date: 13-08-2019 Through 15-08-2019",
year = "2019",
doi = "10.1117/12.2525997",
language = "English",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Bert Muller and Ge Wang",
booktitle = "Developments in X-Ray Tomography XII",
address = "United States",
}