TY - JOUR
T1 - Diagnostic and Prognostic Value of a Type 1 Brugada Electrocardiogram at Higher (Third or Second) V1 to V2 Recording in Men With Brugada Syndrome
AU - Miyamoto, Koji
AU - Yokokawa, Miki
AU - Tanaka, Koji
AU - Nagai, Takayuki
AU - Okamura, Hideo
AU - Noda, Takashi
AU - Satomi, Kazuhiro
AU - Suyama, Kazuhiro
AU - Kurita, Takashi
AU - Aihara, Naohiko
AU - Kamakura, Shiro
AU - Shimizu, Wataru
PY - 2007/1/1
Y1 - 2007/1/1
N2 - To evaluate the diagnostic and prognostic value of an electrocardiogram (ECG) recorded at a higher (third or second) intercostal space, 98 men (17 to 76 years of age, mean ± SD 47 ± 13; with documented ventricular fibrillation [VF] in 22 and syncope in 32) were categorized into 3 groups; 68 men had a spontaneous type 1 ECG in standard leads V1 and V2 (S group), 19 had a spontaneous type 1 ECG only in the higher V1 and V2 leads (H group), and 11 had a type 1 ECG only after receiving class Ic sodium channel blockers (Ic group). There were no significant differences in baseline clinical characteristics, including VF episodes, syncope, atrial fibrillation, family history, late potentials, and inducibility of VF during electrophysiologic study across the 3 groups. During prospective follow-up periods (779 ± 525, 442 ± 282, and 573 ± 382 days, respectively), subsequent cardiac events occurred in 11 men (16%) within the S group, in 2 men (11%) in the H group, and in 0 men (0%) in the Ic group (p = NS, S vs H group). In men with previous episodes of VF, subsequent cardiac events occurred in 7 (44%) within the S group and in 2 (50%) in the H group (p = NS). In conclusion, men with a spontaneous type 1 Brugada ECG recorded only at higher leads V1 and V2 showed a prognosis similar to that of men with a type 1 ECG in using standard leads V1 and V2.
AB - To evaluate the diagnostic and prognostic value of an electrocardiogram (ECG) recorded at a higher (third or second) intercostal space, 98 men (17 to 76 years of age, mean ± SD 47 ± 13; with documented ventricular fibrillation [VF] in 22 and syncope in 32) were categorized into 3 groups; 68 men had a spontaneous type 1 ECG in standard leads V1 and V2 (S group), 19 had a spontaneous type 1 ECG only in the higher V1 and V2 leads (H group), and 11 had a type 1 ECG only after receiving class Ic sodium channel blockers (Ic group). There were no significant differences in baseline clinical characteristics, including VF episodes, syncope, atrial fibrillation, family history, late potentials, and inducibility of VF during electrophysiologic study across the 3 groups. During prospective follow-up periods (779 ± 525, 442 ± 282, and 573 ± 382 days, respectively), subsequent cardiac events occurred in 11 men (16%) within the S group, in 2 men (11%) in the H group, and in 0 men (0%) in the Ic group (p = NS, S vs H group). In men with previous episodes of VF, subsequent cardiac events occurred in 7 (44%) within the S group and in 2 (50%) in the H group (p = NS). In conclusion, men with a spontaneous type 1 Brugada ECG recorded only at higher leads V1 and V2 showed a prognosis similar to that of men with a type 1 ECG in using standard leads V1 and V2.
UR - http://www.scopus.com/inward/record.url?scp=33845703948&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33845703948&partnerID=8YFLogxK
U2 - 10.1016/j.amjcard.2006.07.062
DO - 10.1016/j.amjcard.2006.07.062
M3 - Article
C2 - 17196462
AN - SCOPUS:33845703948
SN - 0002-9149
VL - 99
SP - 53
EP - 57
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 1
ER -