Diagnostic criteria, severity classification and guidelines of localized scleroderma

Yoshihide Asano, Manabu Fujimoto, Osamu Ishikawa, Shinichi Sato, Masatoshi Jinnin, Kazuhiko Takehara, Minoru Hasegawa, Toshiyuki Yamamoto, Hironobu Ihn

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)


We established diagnostic criteria and severity classification of localized scleroderma because there is no established diagnostic criteria or widely accepted severity classification of the disease. Also, there has been no clinical guideline for localized scleroderma, so we established its clinical guideline ahead of all over the world. In particular, the clinical guideline was established by clinical questions based on evidence-based medicine according to the New Minds Clinical Practice Guideline Creation Manual (version 1.0). We aimed to make the guideline easy to use and reliable based on the newest evidence, and to present guidance as specific as possible for various clinical problems in treatment of localized scleroderma.

Original languageEnglish
Pages (from-to)755-780
Number of pages26
JournalJournal of Dermatology
Issue number7
Publication statusPublished - 2018 Jul
Externally publishedYes


  • diagnostic criteria
  • guideline
  • localized scleroderma
  • severity classification
  • treatment

ASJC Scopus subject areas

  • Dermatology


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