Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome: A case with double lung cancers

Kumi Takahashi; Takashi Ishida; Go Ogura; Taeko Ishii; Kengo Oshima; Suguru Sato; Miho Muroi; Kenya Kanazawa; Junpei Saito.; Yoshinori Otsuka; Kazuo Watanabe; Makoto Handa; Mitsuru Munakata

doi:10.2169/internalmedicine.43.972

Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome: A case with double lung cancers

Kumi Takahashi, Takashi Ishida, Go Ogura, Taeko Ishii, Kengo Oshima, Suguru Sato, Miho Muroi, Kenya Kanazawa, Junpei Saito., Yoshinori Otsuka, Kazuo Watanabe, Makoto Handa, Mitsuru Munakata

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A 65-year-old man was admitted to our hospital because of dyspnea on exertion. He had oculocutaneous albinism innately and his parents were consanguineous. His chest roentgenogram on admission showed reticulonodular infiltrates and cystic changes throughout both lung fields, and 7 cm mass in the left middle field. Cytology of bronchoalveolar lavage fluid (BALF) revealed macrophages containing ceroid. The diagnosis of HPS was made clinically and the tumor was diagnosed as poorly differentiated adenocarcinoma of the lung. He died of respiratory failure. By autopsy, additional well-differentiated adenocarcinoma was detected. Cytology of BALF was useful to confirm ceroid accumulation in the lung.

Original language	English
Pages (from-to)	972-976
Number of pages	5
Journal	Internal Medicine
Volume	43
Issue number	10
DOIs	https://doi.org/10.2169/internalmedicine.43.972
Publication status	Published - 2004 Oct
Externally published	Yes

Keywords

Ceroid
Interstitial Pneumonia
Lung cancer
Oculocutaneous albinism

ASJC Scopus subject areas

Internal Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2169/internalmedicine.43.972

Cite this

@article{b569cb9d90e048fc8b5d0ba6a9e61093,

title = "Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome: A case with double lung cancers",

abstract = "A 65-year-old man was admitted to our hospital because of dyspnea on exertion. He had oculocutaneous albinism innately and his parents were consanguineous. His chest roentgenogram on admission showed reticulonodular infiltrates and cystic changes throughout both lung fields, and 7 cm mass in the left middle field. Cytology of bronchoalveolar lavage fluid (BALF) revealed macrophages containing ceroid. The diagnosis of HPS was made clinically and the tumor was diagnosed as poorly differentiated adenocarcinoma of the lung. He died of respiratory failure. By autopsy, additional well-differentiated adenocarcinoma was detected. Cytology of BALF was useful to confirm ceroid accumulation in the lung.",

keywords = "Ceroid, Interstitial Pneumonia, Lung cancer, Oculocutaneous albinism",

author = "Kumi Takahashi and Takashi Ishida and Go Ogura and Taeko Ishii and Kengo Oshima and Suguru Sato and Miho Muroi and Kenya Kanazawa and Junpei Saito. and Yoshinori Otsuka and Kazuo Watanabe and Makoto Handa and Mitsuru Munakata",

year = "2004",

month = oct,

doi = "10.2169/internalmedicine.43.972",

language = "English",

volume = "43",

pages = "972--976",

journal = "Internal Medicine",

issn = "0918-2918",

publisher = "Japanese Society of Internal Medicine",

number = "10",

}

TY - JOUR

T1 - Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome

T2 - A case with double lung cancers

AU - Takahashi, Kumi

AU - Ishida, Takashi

AU - Ogura, Go

AU - Ishii, Taeko

AU - Oshima, Kengo

AU - Sato, Suguru

AU - Muroi, Miho

AU - Kanazawa, Kenya

AU - Saito., Junpei

AU - Otsuka, Yoshinori

AU - Watanabe, Kazuo

AU - Handa, Makoto

AU - Munakata, Mitsuru

PY - 2004/10

Y1 - 2004/10

N2 - A 65-year-old man was admitted to our hospital because of dyspnea on exertion. He had oculocutaneous albinism innately and his parents were consanguineous. His chest roentgenogram on admission showed reticulonodular infiltrates and cystic changes throughout both lung fields, and 7 cm mass in the left middle field. Cytology of bronchoalveolar lavage fluid (BALF) revealed macrophages containing ceroid. The diagnosis of HPS was made clinically and the tumor was diagnosed as poorly differentiated adenocarcinoma of the lung. He died of respiratory failure. By autopsy, additional well-differentiated adenocarcinoma was detected. Cytology of BALF was useful to confirm ceroid accumulation in the lung.

AB - A 65-year-old man was admitted to our hospital because of dyspnea on exertion. He had oculocutaneous albinism innately and his parents were consanguineous. His chest roentgenogram on admission showed reticulonodular infiltrates and cystic changes throughout both lung fields, and 7 cm mass in the left middle field. Cytology of bronchoalveolar lavage fluid (BALF) revealed macrophages containing ceroid. The diagnosis of HPS was made clinically and the tumor was diagnosed as poorly differentiated adenocarcinoma of the lung. He died of respiratory failure. By autopsy, additional well-differentiated adenocarcinoma was detected. Cytology of BALF was useful to confirm ceroid accumulation in the lung.

KW - Ceroid

KW - Interstitial Pneumonia

KW - Lung cancer

KW - Oculocutaneous albinism

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U2 - 10.2169/internalmedicine.43.972

DO - 10.2169/internalmedicine.43.972

M3 - Article

C2 - 15575250

AN - SCOPUS:8844222722

SN - 0918-2918

VL - 43

SP - 972

EP - 976

JO - Internal Medicine

JF - Internal Medicine

IS - 10

ER -

Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome: A case with double lung cancers

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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