@article{569c3ee797ce4874b13eadde2714102b,
title = "Diastereoselective and enantioselective glyoxylate-ene reaction catalyzed by new class of binaphthol-derived titanium complex",
abstract = "Diastereo- and enantioselective carbonyl-ene reaction of glyoxylate (2) with trisubstituted olefins (3) catalyzed by chiral titanium complexes (1a), derived from 6,6′-dibromo-1,1′-bi-2-naphthol and diisopropoxytitanium dihalides, is found to provide syn-diastereomers exclusively along with a high level of enantioselectivity.",
author = "Masahiro Terada and Yukihiro Motoyama and Koichi Mikami",
note = "Funding Information: In summary, we have disclosed herein the designed binaphthyl-derived chiral titanium complex (la) as a new type of efficient catalyst for syn-diastereoselective and enantioselective glyoxylate-ene reactions. The key to success is the modification at the 6 position of binaphthol by electron withdrawing group, bromide, in controlling the conformation of binaphthyl rings. Further work along this line is now under investigation.9 Acknowledgment: We are grateful to Dr. Masatoshi Kawashima in Kankyo Kagaku Center Co., Ltd. for generously providing (q-6,6{\textquoteright}-dibromo-1 ,l{\textquoteright}-biQ-naphthol. This research was partially supported by the Grant-in-Aid for Scientific Research on Priority Area No. 05234210 from the Ministry of Education, Science and Culture, Japan, and the Kurata Foundation.",
year = "1994",
month = sep,
day = "5",
doi = "10.1016/S0040-4039(00)73470-8",
language = "English",
volume = "35",
pages = "6693--6696",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd.",
number = "36",
}