The article discusses DIBALH-mediated reductive ring-expansion reaction of cyclic ketoxime. In contrast to the Beckmann rearrangement, the two possible geometries of the oxime C–N double bond can give exclusively an aromatic secondary amine in the presented method.
- 1-indanone oxime
- Beckmann rearrangement
- Chemical-specific hazards
- Reductive ring-expansion reaction
- Ring-expansion reaction