Difference in autonomic nervous effect of blue light depending on the angle of incidence on the eye

Emi Yuda, Yutaka Yoshida, Norihiro Ueda, Junichiro Hayano

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Objective: Blue light has been attributed to the adverse biological effects caused by the use of smartphones and tablet devices at night. However, it is not realistic to immediately avoid nighttime exposure to blue light in the lifestyle of modern society, so other effective methods should be investigated. Earlier studies reported that inferior retinal light exposure causes greater melatonin suppression than superior retinal exposure. We examined whether the autonomic responses to blue light depends on the angle of incidence to the eye. Results: In eight healthy subjects, blue light from organic electroluminescent lighting device (15.4 lx at subjects' eye) was exposed from 6 angles (0º, 30º, 45º, 135º, 150º, and 180º) for 5 min each with a 10-min interval of darkness. After adjusting the order effect of angles, however, no significant difference in heart rate or autonomic indices of heart rate variability with the angle of incidence was detected in this study.

Original languageEnglish
Article number141
JournalBMC Research Notes
Issue number1
Publication statusPublished - 2020 Mar 10


  • Autonomic nervous system
  • Blue light
  • Intrinsically-photosensitive retinal ganglion cell
  • Light-emitting diode
  • Non-image forming function
  • Smartphone
  • Solid-state lighting


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