TY - JOUR
T1 - Difficulties in Diagnosis and Treatment of Asthma in the Elderly
AU - Ohrui, Takashi
AU - Yamaya, Mutsuo
AU - Yanai, Masaru
AU - Sasaki, Hidetada
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2001
Y1 - 2001
N2 - The cause of the high asthma mortality in the elderly is not exactly known. We measured intrabronchial pressures in elderly asthma patients who had long-standing asthma and compared them with those in newly-diagnosed asthma and young healthy volunteers. In elderly asthmatics, at baseline conditions, both central and peripheral airway resistances were significantly higher compared with those in the other groups, which may partly explain the high asthma mortality in the elderly. We report a case of severe acute asthma associated with disturbed consciousness, in which asthma-induced cerebral swelling was considered to be accompanied by neuronal damage, after examination of cerebrospinal fluid. Inhaled steroid is essential for the treatment of moderate to severe asthma. However, approximately 40% of the elderly patients in this category did not use inhaled steroid. Physicians should strongly recommend the use of inhaled steroid to prevent asthma death in elderly asthma patients.
AB - The cause of the high asthma mortality in the elderly is not exactly known. We measured intrabronchial pressures in elderly asthma patients who had long-standing asthma and compared them with those in newly-diagnosed asthma and young healthy volunteers. In elderly asthmatics, at baseline conditions, both central and peripheral airway resistances were significantly higher compared with those in the other groups, which may partly explain the high asthma mortality in the elderly. We report a case of severe acute asthma associated with disturbed consciousness, in which asthma-induced cerebral swelling was considered to be accompanied by neuronal damage, after examination of cerebrospinal fluid. Inhaled steroid is essential for the treatment of moderate to severe asthma. However, approximately 40% of the elderly patients in this category did not use inhaled steroid. Physicians should strongly recommend the use of inhaled steroid to prevent asthma death in elderly asthma patients.
KW - Asthma mortality
KW - Inhaled steroids
KW - Intrabronchial pressures
KW - Near-fatal asthma
KW - Persistent Airway inflammation
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U2 - 10.3143/geriatrics.38.743
DO - 10.3143/geriatrics.38.743
M3 - Article
C2 - 11774711
AN - SCOPUS:0035515702
SN - 0300-9173
VL - 38
SP - 743
EP - 746
JO - Japanese Journal of Geriatrics
JF - Japanese Journal of Geriatrics
IS - 6
ER -