Diffuse bone marrow uptake on F-18 FDG PET in patients with myelodysplastic syndromes

Kentaro Inoue; Ken Okada; Hideo Harigae; Yasuyuki Taki; Ryoi Goto; Shigeo Kinomura; Shunsuke Kato; Tomohiro Kaneta; Hiroshi Fukuda

doi:10.1097/01.rlu.0000242685.55001.67

Diffuse bone marrow uptake on F-18 FDG PET in patients with myelodysplastic syndromes

Kentaro Inoue, Ken Okada, Hideo Harigae, Yasuyuki Taki, Ryoi Goto, Shigeo Kinomura, Shunsuke Kato, Tomohiro Kaneta, Hiroshi Fukuda

Tohoku University

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

It is well known that hematopoietic cytokine stimulation can cause diffuse increase of FDG accumulation in bone marrow on PET imaging, which simulates that seen in patients with bone marrow metastases. However, diffuse bone marrow FDG uptake can be caused by other etiologies. We report 2 patients who did not have a history of hematopoietic cytokine stimulation. The FDG PET images showed diffuse bone marrow FDG uptake, and the patients were diagnosed as having myelodysplastic syndromes. These cases demonstrate that diffuse FDG uptake by bone marrow can suggest neoplastic disease of the hematopoietic tissues.

Original language	English
Pages (from-to)	721-723
Number of pages	3
Journal	Clinical Nuclear Medicine
Volume	31
Issue number	11
DOIs	https://doi.org/10.1097/01.rlu.0000242685.55001.67
Publication status	Published - 2006 Nov

Keywords

Bone marrow
FDG
MDS
Myelodysplastic syndrome
PET

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abstract = "It is well known that hematopoietic cytokine stimulation can cause diffuse increase of FDG accumulation in bone marrow on PET imaging, which simulates that seen in patients with bone marrow metastases. However, diffuse bone marrow FDG uptake can be caused by other etiologies. We report 2 patients who did not have a history of hematopoietic cytokine stimulation. The FDG PET images showed diffuse bone marrow FDG uptake, and the patients were diagnosed as having myelodysplastic syndromes. These cases demonstrate that diffuse FDG uptake by bone marrow can suggest neoplastic disease of the hematopoietic tissues.",

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AU - Okada, Ken

AU - Harigae, Hideo

AU - Taki, Yasuyuki

AU - Goto, Ryoi

AU - Kinomura, Shigeo

AU - Kato, Shunsuke

AU - Kaneta, Tomohiro

AU - Fukuda, Hiroshi

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AB - It is well known that hematopoietic cytokine stimulation can cause diffuse increase of FDG accumulation in bone marrow on PET imaging, which simulates that seen in patients with bone marrow metastases. However, diffuse bone marrow FDG uptake can be caused by other etiologies. We report 2 patients who did not have a history of hematopoietic cytokine stimulation. The FDG PET images showed diffuse bone marrow FDG uptake, and the patients were diagnosed as having myelodysplastic syndromes. These cases demonstrate that diffuse FDG uptake by bone marrow can suggest neoplastic disease of the hematopoietic tissues.

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Diffuse bone marrow uptake on F-18 FDG PET in patients with myelodysplastic syndromes

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