Direct observation of a target cell of the leaf-closing factor by using novel fluorescence-labeled phyllanthurinolactone

Hirotaka Sato; Masayoshi Inada; Takanori Sugimoto; Nobuki Kato; Minoru Ueda

doi:10.1016/j.tetlet.2005.06.044

Direct observation of a target cell of the leaf-closing factor by using novel fluorescence-labeled phyllanthurinolactone

Hirotaka Sato, Masayoshi Inada, Takanori Sugimoto, Nobuki Kato, Minoru Ueda

SCI - Chemistry

Tohoku University

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

We report the synthesis of the fluorescence-labeled probe 2 based on phyllanthurinolactone 1, which is a leaf-closing substance of Phyllanthus urinaria L. Bioorganic studies using probe 2 showed leaf-closing activity at 1 × 10^-5 M, which was one-hundredth of that of the natural product 1. The fluorescence study using 2 revealed that the target cell for 1 is a motor cell and suggested that some receptors for 1 exist on the plasma membrane of the motor cell as with leaf-opening substances.

Original language	English
Pages (from-to)	5537-5541
Number of pages	5
Journal	Tetrahedron Letters
Volume	46
Issue number	33
DOIs	https://doi.org/10.1016/j.tetlet.2005.06.044
Publication status	Published - 2005 Aug 15

Keywords

Fluorescence
Glycosidation
Leaf-closing substance
Mitsunobu reaction
Motor cell
Nyctinasty
Probe compound

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10.1016/j.tetlet.2005.06.044

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@article{32e049c7fb824367b458e9cf0c34448a,

title = "Direct observation of a target cell of the leaf-closing factor by using novel fluorescence-labeled phyllanthurinolactone",

abstract = "We report the synthesis of the fluorescence-labeled probe 2 based on phyllanthurinolactone 1, which is a leaf-closing substance of Phyllanthus urinaria L. Bioorganic studies using probe 2 showed leaf-closing activity at 1 × 10-5 M, which was one-hundredth of that of the natural product 1. The fluorescence study using 2 revealed that the target cell for 1 is a motor cell and suggested that some receptors for 1 exist on the plasma membrane of the motor cell as with leaf-opening substances.",

keywords = "Fluorescence, Glycosidation, Leaf-closing substance, Mitsunobu reaction, Motor cell, Nyctinasty, Probe compound",

author = "Hirotaka Sato and Masayoshi Inada and Takanori Sugimoto and Nobuki Kato and Minoru Ueda",

note = "Funding Information: This work was supported by the Ministry of Education, Science, Sports and Culture (Japan) Grant-in-Aid for Scientific Research (No. 15681013) and Grant-in-Aid for the 21st Century COE program of Tohoku University from the Ministry of Education, Culture, Sports, Science, and Technology, Japan.",

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doi = "10.1016/j.tetlet.2005.06.044",

language = "English",

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journal = "Tetrahedron Letters",

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T1 - Direct observation of a target cell of the leaf-closing factor by using novel fluorescence-labeled phyllanthurinolactone

AU - Sato, Hirotaka

AU - Inada, Masayoshi

AU - Sugimoto, Takanori

AU - Kato, Nobuki

AU - Ueda, Minoru

N1 - Funding Information: This work was supported by the Ministry of Education, Science, Sports and Culture (Japan) Grant-in-Aid for Scientific Research (No. 15681013) and Grant-in-Aid for the 21st Century COE program of Tohoku University from the Ministry of Education, Culture, Sports, Science, and Technology, Japan.

PY - 2005/8/15

Y1 - 2005/8/15

N2 - We report the synthesis of the fluorescence-labeled probe 2 based on phyllanthurinolactone 1, which is a leaf-closing substance of Phyllanthus urinaria L. Bioorganic studies using probe 2 showed leaf-closing activity at 1 × 10-5 M, which was one-hundredth of that of the natural product 1. The fluorescence study using 2 revealed that the target cell for 1 is a motor cell and suggested that some receptors for 1 exist on the plasma membrane of the motor cell as with leaf-opening substances.

AB - We report the synthesis of the fluorescence-labeled probe 2 based on phyllanthurinolactone 1, which is a leaf-closing substance of Phyllanthus urinaria L. Bioorganic studies using probe 2 showed leaf-closing activity at 1 × 10-5 M, which was one-hundredth of that of the natural product 1. The fluorescence study using 2 revealed that the target cell for 1 is a motor cell and suggested that some receptors for 1 exist on the plasma membrane of the motor cell as with leaf-opening substances.

KW - Fluorescence

KW - Glycosidation

KW - Leaf-closing substance

KW - Mitsunobu reaction

KW - Motor cell

KW - Nyctinasty

KW - Probe compound

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DO - 10.1016/j.tetlet.2005.06.044

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SN - 0040-4039

VL - 46

SP - 5537

EP - 5541

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 33

ER -

Direct observation of a target cell of the leaf-closing factor by using novel fluorescence-labeled phyllanthurinolactone

Abstract

Keywords

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