Carbohydrates bind proteins multivalently to enhance the affinity between them. This multivalent interaction called a glycoside cluster effect has received much attention from not only carbohydrate chemists but also medicinal and natural product chemists. Herein the recent progress of the drug discovery research using a cluster effect is reviewed.
|Number of pages
|Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
|Published - 2015 Apr