Dynamic response of the pulmonary circulation in continuous flow artificial heart systems

P. S. Olegario, M. Yoshizawa, A. Tanaka, Y. Shiraishi, D. Ogawa, T. Hanaoka, K. Abe, T. Yambe, S. Nitta

Research output: Contribution to journalConference articlepeer-review

Abstract

Pulmonary circulation dynamics is important when considering bi-ventricular assist devices (BiVAD) or total artificial heart (TAH) systems and in investigating the mechanism of atrial collapse in order to design better control algorithms. In this study, we investigated pulmonary circulation dynamics in a continuous flow artificial heart system by performing acute tests on a mature goat. By varying the right pump speed, we were able to observe the dynamic response of the left atrial pressure (LAP) and simulate conditions that result in atrial suction. The results showed a time constant characteristic of a compliance lag in LAP response to changes in right pump output in the TAH configuration. These results may prove useful in the design of a new mock circulatory system that incorporates the dynamics of the pulmonary circulation, and in the improvement of existing control algorithms that prevent atrial wall collapse.

Original languageEnglish
Pages (from-to)3777-3780
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume26 V
DOIs
Publication statusPublished - 2004
EventConference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004 - San Francisco, CA, United States
Duration: 2004 Sept 12004 Sept 5

Keywords

  • Artificial heart
  • Atrial collapse
  • Continuous flow pump

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