Dynamics of nano-meter-sized domains on a vesicle

Y. Sakuma, N. Urakami, Y. Ogata, M. Nagao, S. Komura, M. Imai

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We have investigated the dynamics of nano-meter-sized domains on a vesicle composed of saturated phospholipids, unsaturated phospholipids and cholesterols by means of a neutron spin echo technique. The diffusion coeffisient of the domains obtained from the intermediate scattering function is about two orders of magnitude larger than that calculated by Saffman and Delbrück law. From molecular dynamics simulations we found another type of the domain dynamics where the domains are agitated by thermal fluctuation and repeats coalescence and rupture. The relaxation rate of the new mode is about two orders of magnitude larger than that of the diffusion mode. The coalescence and rupture mode of domains may be responsible for the observed domain dynamics.

Original languageEnglish
Title of host publicationComplex Systems - 5th International Workshop on Complex Systems
Pages717-720
Number of pages4
DOIs
Publication statusPublished - 2008
Event5th International Workshop on Complex Systems - Sendai, Japan
Duration: 2007 Sept 252007 Sept 28

Publication series

NameAIP Conference Proceedings
Volume982
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference5th International Workshop on Complex Systems
Country/TerritoryJapan
CitySendai
Period07/9/2507/9/28

Keywords

  • Domain dynamics
  • Lipid raft
  • Nano-meter-sized domain
  • Neutron spin echo
  • Small unilamellar vesicle

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