TY - JOUR
T1 - Effect of denture adhesives on oral moisture
T2 - A multicenter randomized controlled trial
AU - Nishi, Yasuhiro
AU - Nomura, Taro
AU - Murakami, Mamoru
AU - Kawai, Yasuhiko
AU - Nishimura, Masahiro
AU - Kondo, Hisatomo
AU - Ito, Yoshihiko
AU - Tsuboi, Akito
AU - Hong, Guang
AU - Kimoto, Suguru
AU - Gunji, Atsuko
AU - Suzuki, Asako
AU - Ohwada, Gaku
AU - Minakuchi, Shunsuke
AU - Sato, Yusuke
AU - Suzuki, Tetsuya
AU - Kimoto, Katsuhiko
AU - Hoshi, Noriyuki
AU - Saita, Makiko
AU - Yoneyama, Yoshikazu
AU - Sato, Yohei
AU - Morokuma, Masakazu
AU - Okazaki, Joji
AU - Maeda, Takeshi
AU - Nakai, Kenichiro
AU - Ichikawa, Tetsuo
AU - Nagao, Kan
AU - Fujimoto, Keiko
AU - Murata, Hiroshi
AU - Kurogi, Tadafumi
AU - Yoshida, Kazuhiro
AU - Hosoi, Toshio
AU - Hamada, Taizo
N1 - Funding Information:
The authors wish to thank the study collaborators. The authors are also grateful to all individuals who participated in the study. This study was supported by a Grant-in-Aid for Scientific Research (B) (No. 24390439 ) from the Japan Society for the Promotion of Science .
Publisher Copyright:
© 2019
PY - 2020/7
Y1 - 2020/7
N2 - Purpose: The purpose of this study was to investigate the effect of denture adhesives on oral moisture in a 10-center parallel randomized clinical trial. Methods: Two hundred edentulous subjects wearing complete dentures were allocated into three groups: cream-type adhesive, powder-type adhesive and control groups. The adhesives (and saline solution in the control group) were applied to the mucosal surface of the dentures for 4 days, and baseline data and data after the intervention for eight meals over 4 days were obtained. For the main outcome, oral moisture was measured with a moisture checking device. Secondary outcomes were denture satisfaction, masticatory performance, denture retention, and occlusal force. In addition to between-group and within-group comparisons of oral moisture, investigations for secondary outcomes were undertaken in subgroups classified according to the degree of oral moisture at baseline (normal subgroup and dry mouth subgroup). Intention-to-treat analysis was also performed. Results: Between-group and within-group comparisons of oral moisture showed no significant differences. The cream-type and powder-type denture adhesives were significantly effective in the dry mouth group for denture satisfaction ratings of ability to masticate, stability, retention, and comfort of mandibular dentures (p < 0.05). The masticatory performance and retentive force of the dry mouth denture adhesive using groups were significantly improved after intervention (p < 0.05). Conclusions: The oral moisture of complete denture wearers was not influenced by the use of denture adhesives. Our findings showed that denture adhesives improved subjective denture satisfaction, masticatory performance, and retention for complete denture patients with oral dryness.
AB - Purpose: The purpose of this study was to investigate the effect of denture adhesives on oral moisture in a 10-center parallel randomized clinical trial. Methods: Two hundred edentulous subjects wearing complete dentures were allocated into three groups: cream-type adhesive, powder-type adhesive and control groups. The adhesives (and saline solution in the control group) were applied to the mucosal surface of the dentures for 4 days, and baseline data and data after the intervention for eight meals over 4 days were obtained. For the main outcome, oral moisture was measured with a moisture checking device. Secondary outcomes were denture satisfaction, masticatory performance, denture retention, and occlusal force. In addition to between-group and within-group comparisons of oral moisture, investigations for secondary outcomes were undertaken in subgroups classified according to the degree of oral moisture at baseline (normal subgroup and dry mouth subgroup). Intention-to-treat analysis was also performed. Results: Between-group and within-group comparisons of oral moisture showed no significant differences. The cream-type and powder-type denture adhesives were significantly effective in the dry mouth group for denture satisfaction ratings of ability to masticate, stability, retention, and comfort of mandibular dentures (p < 0.05). The masticatory performance and retentive force of the dry mouth denture adhesive using groups were significantly improved after intervention (p < 0.05). Conclusions: The oral moisture of complete denture wearers was not influenced by the use of denture adhesives. Our findings showed that denture adhesives improved subjective denture satisfaction, masticatory performance, and retention for complete denture patients with oral dryness.
KW - Denture adhesive
KW - Moisture-checker
KW - Oral moisture
KW - RCT
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U2 - 10.1016/j.jpor.2019.08.004
DO - 10.1016/j.jpor.2019.08.004
M3 - Article
C2 - 31501069
AN - SCOPUS:85071848752
SN - 1883-1958
VL - 64
SP - 281
EP - 288
JO - Nippon Hotetsu Shika Gakkai zasshi
JF - Nippon Hotetsu Shika Gakkai zasshi
IS - 3
ER -