TY - GEN
T1 - Effect of Isoelectric point on enzyme immobilization property of magnetic apatite microcapsules encapsulating maghemite
AU - Yamamoto, Masaya
AU - Yabutsuka, Takeshi
AU - Takai, Shigeomi
AU - Yao, Takeshi
N1 - Publisher Copyright:
© 2017 Trans Tech Publications, Switzerland.
PY - 2017
Y1 - 2017
N2 - It is well-known that apatite has high affinity to many kinds of biomolecules. In this study, the authors aimed to develop the apatite microcapsules with both enzyme immobilization property by the bioaffinity of apatite and magnetism of core materials. The authors encapsulated maghemite particles, possesing ferrimagnetism, with apatite by attaching Apatite Nuclei on the surfaces of maghemite particles and subsequently immersing them in SBF. To evaluate performance of the microcapsules as enzyme immobilization carriers, the authors investigated enzyme immobilization property of the microcapsules fabricated by biomimetic method using Apatite Nuclei and SBF from the viewpoint of the difference of isoelectric point of the three-Types of enzymes.
AB - It is well-known that apatite has high affinity to many kinds of biomolecules. In this study, the authors aimed to develop the apatite microcapsules with both enzyme immobilization property by the bioaffinity of apatite and magnetism of core materials. The authors encapsulated maghemite particles, possesing ferrimagnetism, with apatite by attaching Apatite Nuclei on the surfaces of maghemite particles and subsequently immersing them in SBF. To evaluate performance of the microcapsules as enzyme immobilization carriers, the authors investigated enzyme immobilization property of the microcapsules fabricated by biomimetic method using Apatite Nuclei and SBF from the viewpoint of the difference of isoelectric point of the three-Types of enzymes.
KW - Apatite microcapsules
KW - Apatite Nuclei
KW - Enzyme immobilization
KW - Maghemite
KW - Magnetic property
UR - http://www.scopus.com/inward/record.url?scp=85034961819&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85034961819&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.758.178
DO - 10.4028/www.scientific.net/KEM.758.178
M3 - Conference contribution
AN - SCOPUS:85034961819
SN - 9783035712209
T3 - Key Engineering Materials
SP - 178
EP - 183
BT - Bioceramics - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine
A2 - Rey, Christian
A2 - Combes, Christele
A2 - Drouet, Christophe
PB - Trans Tech Publications Ltd
T2 - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2017
Y2 - 25 October 2017 through 27 October 2017
ER -