Effect of underwear made from MEDIELE® on skin barrier function of atopic dermatitis patients in winter season

Maki Ozawa; Ikuko Numata; Akiko Watabe; Hiroko Koizumi; Ai Memezawa; Katsuko Kikuchi; Setsuya Aiba

Effect of underwear made from MEDIELE® on skin barrier function of atopic dermatitis patients in winter season

Maki Ozawa, Ikuko Numata, Akiko Watabe, Hiroko Koizumi, Ai Memezawa, Katsuko Kikuchi, Setsuya Aiba

Research output: Contribution to journal › Article › peer-review

Abstract

We compared the effects of underwear made from ethylene-vinyl alcohol copolymer fiber (MEDIELE®) with those made from cotton on skin condition of atopic dermatitis patients in winter season. This was a randomized, single-blind, crossover study in which the subjects consecutively wore MEDIELE® and cotton underwear for 4 weeks each. Local SCORAD, skin conductance and transepidermal water loss (TEWL) were measured on the scapular region. There was no difference in local SCORAD and the skin conductance values. An increase of the TEWL value was observed at the endpoint of wearing cotton underwear. On the other hand, the TEWL value was maintained at the same level during the period of wearing MEDIELE® underwear. Therefore, we concluded the underwear made from MEDIELE® was useful in maintaining skin barrier function of atopic dermatitis patients in winter season.

Original language	English
Pages (from-to)	475-481
Number of pages	7
Journal	Skin Research
Volume	7
Issue number	4
Publication status	Published - 2008 Aug

Keywords

Atopic dermatitis
Barrier function
Stratum corneum
TEWL
Underwear

ASJC Scopus subject areas

Dermatology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Effect of underwear made from MEDIELE{\textregistered} on skin barrier function of atopic dermatitis patients in winter season",

abstract = "We compared the effects of underwear made from ethylene-vinyl alcohol copolymer fiber (MEDIELE{\textregistered}) with those made from cotton on skin condition of atopic dermatitis patients in winter season. This was a randomized, single-blind, crossover study in which the subjects consecutively wore MEDIELE{\textregistered} and cotton underwear for 4 weeks each. Local SCORAD, skin conductance and transepidermal water loss (TEWL) were measured on the scapular region. There was no difference in local SCORAD and the skin conductance values. An increase of the TEWL value was observed at the endpoint of wearing cotton underwear. On the other hand, the TEWL value was maintained at the same level during the period of wearing MEDIELE{\textregistered} underwear. Therefore, we concluded the underwear made from MEDIELE{\textregistered} was useful in maintaining skin barrier function of atopic dermatitis patients in winter season.",

keywords = "Atopic dermatitis, Barrier function, Stratum corneum, TEWL, Underwear",

author = "Maki Ozawa and Ikuko Numata and Akiko Watabe and Hiroko Koizumi and Ai Memezawa and Katsuko Kikuchi and Setsuya Aiba",

year = "2008",

month = aug,

language = "English",

volume = "7",

pages = "475--481",

journal = "Skin Research",

issn = "1347-1813",

publisher = "Osaka University",

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TY - JOUR

T1 - Effect of underwear made from MEDIELE® on skin barrier function of atopic dermatitis patients in winter season

AU - Ozawa, Maki

AU - Numata, Ikuko

AU - Watabe, Akiko

AU - Koizumi, Hiroko

AU - Memezawa, Ai

AU - Kikuchi, Katsuko

AU - Aiba, Setsuya

PY - 2008/8

Y1 - 2008/8

N2 - We compared the effects of underwear made from ethylene-vinyl alcohol copolymer fiber (MEDIELE®) with those made from cotton on skin condition of atopic dermatitis patients in winter season. This was a randomized, single-blind, crossover study in which the subjects consecutively wore MEDIELE® and cotton underwear for 4 weeks each. Local SCORAD, skin conductance and transepidermal water loss (TEWL) were measured on the scapular region. There was no difference in local SCORAD and the skin conductance values. An increase of the TEWL value was observed at the endpoint of wearing cotton underwear. On the other hand, the TEWL value was maintained at the same level during the period of wearing MEDIELE® underwear. Therefore, we concluded the underwear made from MEDIELE® was useful in maintaining skin barrier function of atopic dermatitis patients in winter season.

AB - We compared the effects of underwear made from ethylene-vinyl alcohol copolymer fiber (MEDIELE®) with those made from cotton on skin condition of atopic dermatitis patients in winter season. This was a randomized, single-blind, crossover study in which the subjects consecutively wore MEDIELE® and cotton underwear for 4 weeks each. Local SCORAD, skin conductance and transepidermal water loss (TEWL) were measured on the scapular region. There was no difference in local SCORAD and the skin conductance values. An increase of the TEWL value was observed at the endpoint of wearing cotton underwear. On the other hand, the TEWL value was maintained at the same level during the period of wearing MEDIELE® underwear. Therefore, we concluded the underwear made from MEDIELE® was useful in maintaining skin barrier function of atopic dermatitis patients in winter season.

KW - Atopic dermatitis

KW - Barrier function

KW - Stratum corneum

KW - TEWL

KW - Underwear

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SN - 1347-1813

VL - 7

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JO - Skin Research

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ER -

Effect of underwear made from MEDIELE® on skin barrier function of atopic dermatitis patients in winter season

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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