TY - JOUR
T1 - Effectiveness and safety of a new dental plaque removal device utilizing micro mist spray for removing oral biofilm in vitro
AU - Hihara, Hiroki
AU - Tagaino, Ryo
AU - Washio, Jumpei
AU - Laosuwan, Kittipong
AU - Wicaksono, Dimas Prasetianto
AU - Izumita, Kuniyuki
AU - Koide, Rie
AU - Takahashi, Nobuhiro
AU - Sasaki, Keiichi
N1 - Funding Information:
This work was supported by Japan Agency for Medical Research and Development (AMED) Grant Number JP 19he1302008, J. MORITA MFG. CORP (Kyoto, Japan), and Japan Society for the Promotion of Science (JSPS) Grants-in-Aid for Scientific Research Grant Number JP 20K10027.
Funding Information:
We are deeply grateful to Prof. Maruyama (National Institute of Technology, Hachinohe College), Prof. Y. Iga, Prof. J. Ishimoto, Prof. M. Ohta, Prof. T. Sato, Dr. J. Okajima, Dr. S. Uehara, Mr. S. Moriya (Institute of Fluid Science, Tohoku University), Dr. K. Ezoe and Dr. S. Sato (Tohoku University Graduate School of Dentistry) for helpful discussions.
Publisher Copyright:
© 2021, The Author(s).
PY - 2021/12
Y1 - 2021/12
N2 - Background: Removal of oral biofilm from the oral mucosa is essential for preventing risk of respiratory and gastrointestinal infection in elderly people. Currently, no device is available which can remove oral biofilm from oral mucosa effectively and safely. Therefore, the effectiveness and safety of the Micro Scale Mist UNIT (MSM-UNIT), a newly developed dental plaque removal device utilizing high speed sprays of fine water droplets, were evaluated for biofilm removal, including the rate and surface roughness for simulated tooth surface and mucous membrane. Methods: Simulated tooth and oral mucosa coated with an artificial biofilm of Streptococcus mutans were used for evaluation of effectiveness, with uncoated substrates as the controls. The MSM-UNIT and a conventional air ablation device were operated under recommended instructions. The effectiveness was evaluated from the rate of removal of the biofilm, and the safety was evaluated from the damage observed by scanning electron microscope and surface roughness. Results: The biofilm removal rate of the MSM-UNIT was significantly higher than that of AIRFLOW. Little damage was observed in the area treated by the MSM-UNIT. The surface roughness of the MSM-UNIT treated area on simulated tooth surface and oral mucosa showed no significant difference to the control area. In contrast, cracks and powder were observed in the area treated by AIRFLOW. In particular, the surface roughness of the AIRFLOW treated area for Toughsilon was significantly larger than that of the control. Conclusions: The MSM-UNIT could be used safely and effectively for removing biofilm not only on simulated tooth surfaces but also simulated mucous membrane. The MSM-UNIT has no harmful effect on teeth or oral mucosa, and may be used for comprehensive oral care for patients during nursing care and the perioperative period.
AB - Background: Removal of oral biofilm from the oral mucosa is essential for preventing risk of respiratory and gastrointestinal infection in elderly people. Currently, no device is available which can remove oral biofilm from oral mucosa effectively and safely. Therefore, the effectiveness and safety of the Micro Scale Mist UNIT (MSM-UNIT), a newly developed dental plaque removal device utilizing high speed sprays of fine water droplets, were evaluated for biofilm removal, including the rate and surface roughness for simulated tooth surface and mucous membrane. Methods: Simulated tooth and oral mucosa coated with an artificial biofilm of Streptococcus mutans were used for evaluation of effectiveness, with uncoated substrates as the controls. The MSM-UNIT and a conventional air ablation device were operated under recommended instructions. The effectiveness was evaluated from the rate of removal of the biofilm, and the safety was evaluated from the damage observed by scanning electron microscope and surface roughness. Results: The biofilm removal rate of the MSM-UNIT was significantly higher than that of AIRFLOW. Little damage was observed in the area treated by the MSM-UNIT. The surface roughness of the MSM-UNIT treated area on simulated tooth surface and oral mucosa showed no significant difference to the control area. In contrast, cracks and powder were observed in the area treated by AIRFLOW. In particular, the surface roughness of the AIRFLOW treated area for Toughsilon was significantly larger than that of the control. Conclusions: The MSM-UNIT could be used safely and effectively for removing biofilm not only on simulated tooth surfaces but also simulated mucous membrane. The MSM-UNIT has no harmful effect on teeth or oral mucosa, and may be used for comprehensive oral care for patients during nursing care and the perioperative period.
KW - Micro scale mist
KW - Oral biofilm
KW - Oral care
KW - Oral mucosa
KW - Translational research
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U2 - 10.1186/s12903-021-01647-4
DO - 10.1186/s12903-021-01647-4
M3 - Article
C2 - 34088301
AN - SCOPUS:85107331515
SN - 1472-6831
VL - 21
JO - BMC Oral Health
JF - BMC Oral Health
IS - 1
M1 - 286
ER -